Recombinant Human CUEDC2, His-tagged

• Cat.No.: CUEDC2-2299H
• Product Overview: Recombinant human CUEDC2 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Protein Length: 310aa
• Description: CUEDC2 belongs to the CUEDC2 family and contains 1 CUE domain. This protein down-regulates ESR1 protein levels through the ubiquitination-proteasome pathway, regardless of the presence of 17 beta-estradiol. It also involves in 17 beta-estradiol-induced ESR1 degradation and controls PGR protein levels through a similar mechanism.
• Form: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 20% glycerol, 1mM DTT.
• Molecular Mass: 34 kDa
• AA Sequence: MGSSHHHHHH SSGLVPRGSH MGSMELERIV SAALLAFVQT HLPEADLSGL DEVIFSYVLG VLEDLGPSGP SEENFDMEAF TEMMEAYVPGFAHIPRGTIG DMMQKLSGQL SDARNKENLQ PQSSGVQGQV PISPEPLQRP EMLKEETRSS AAAAADTQDE ATGAEEELLP GVDVLLEVFP TCSVEQAQWV LAKARGDLEE AVQMLVEGKE EGPAAWEGPN QDLPRRLRGP QKDELKSFIL QKYMMVDSAE DQKIHRPMAP KEAPKKLIRYIDNQVVSTKG ERFKDVRNPE AEEMKATYIN LKPARKYRFH
• Purity: >90% by SDS - PAGE
• Applications: SDS-PAGE
• Storage: Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
• Concentration: 1 mg/ml

Gene Information

• Gene Name: CUEDC2 CUE domain containing 2 [ Homo sapiens ]
• Official Symbol: CUEDC2
• Synonyms: C10orf66; bA18I14.5; CUE domain containing 2; 28352; Ensembl:ENSG00000107874; MGC2491; CUE domain-containing protein 2
• Gene ID: 79004
• mRNA Refseq: NM_024040.2
• Protein Refseq: NP_076945.2
• MIM: 614142
• UniProt ID: Q9H467
• Chromosome Location: 10q24.32
• Function: protein binding