Recombinant Human CUL3/RBX1, GST-tagged
| Cat.No. : | CUL3-240H |
| Product Overview : | Recombinant Human CUL3/RBX1(a.a: CUL3: 2-768(end); Rnx1: 1-108(end)) fused with GST tag at N-terminal was expressed in Insect cells. |
- Specification
- Gene Information
- Related Products
| Description : | Complex of human cullin-3 (CUL3) with human RING box protein 1 (Rbx1), also known as E3 ubiquitin-protein ligase RBX1. CUL3 (a.a. 2-768(end) with N-terminal GSTtag, 117 kDa) is co-expressed with Rbx1 (a.a. 1-108(end), 12 kDa) in a baculovirus infected Sf9 cell expression system. GenBank Accession Nos. are NM_003590 (CUL3) and NM_014248 (Rbx1). |
| Source : | Insect cells |
| Species : | Human |
| Tag : | GST |
| Form : | 40 mM Tris-HCl, pH 8.0, 110 mM NaCl, 2.2 mM KCl, 0.04% Tween-20, 20% glycerol, and 1.6 mM glutathione. |
| Molecular Mass : | CUL3: 117 kDa; Rbx1: 12 kDa |
| Purity : | Purity: ≥72% (CUL3: 66%; RBX1: 6%) |
| Applications : | Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling. |
| Stability : | At least 6 months at –80 centigrade. Avoid freeze/thaw cycles. Storing diluted enzyme is not recommended, if necessary, use carrier protein (BSA 0.1– 0.5%). |
| Storage : | At least 6 months at -80 centigrade |
| Concentration : | 0.13 mg/ml |
| Warning : | Avoid freeze/thaw cycles. Storing diluted enzyme is not recommended, if necessary, use carrier protein (BSA 0.1 – 0.5%). |
| Gene Name : | CUL3 cullin 3 [ Homo sapiens ] |
| Official Symbol : | CUL3 |
| Synonyms : | CUL3; cullin 3; cullin-3; CUL-3; PHA2E; FLJ25665; |
| Gene ID : | 8452 |
| mRNA Refseq : | NM_003590 |
| Protein Refseq : | NP_003581 |
| MIM : | 603136 |
| UniProt ID : | Q13618 |
| Chromosome Location : | 2q36.2 |
| Pathway : | ATF-2 transcription factor network, organism-specific biosystem; Adaptive Immune System, organism-specific biosystem; Antigen processing: Ubiquitination and Proteasome degradation, organism-specific biosystem; Aurora B signaling, organism-specific biosystem; Canonical Wnt signaling pathway, organism-specific biosystem; Class I MHC mediated antigen processing & amp; |
| Function : | cyclin binding; protein binding; ubiquitin protein ligase binding; contributes_to ubiquitin-protein ligase activity; |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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