Active Recombinant Human CXADR Protein, Fc-tagged

• Cat.No.: CXADR-001H
• Product Overview: Recombinant human CXADR (Leu20 - Gly237) protein with a human IgG1 (Pro100 - Lys330) Fc tag at C-terminus was expressed in mouse myeloma cell line. Disulfide-linked homodimer.

Specification

• Description: The protein encoded by this gene is a type I membrane receptor for group B coxsackieviruses and subgroup C adenoviruses. Several transcript variants encoding different isoforms have been found for this gene. Pseudogenes of this gene are found on chromosomes 15, 18, and 21.
• Source: Mammalian cells
• Species: Human
• Tag: Fc
• Predicted N Terminal: Leu20
• Bio-activity: Measured by the ability of the immobilized protein to support the adhesion of human monocyte-derived dendritic cells. When 5 x 10^4 cells/well are added to rhCXADR/Fc Chimera coated plates (10 µg/mL), approximately 25%‑45% will adhere after 30 minutes of
• Molecular Mass: 60-65 kDa, reducing conditions
• Endotoxin: <0.10 EU per 1 μg of the protein by the LAL method.
• Purity: >95%, by SDS-PAGE under reducing conditions and visualized by silver stain.
• Storage: Avoid repeated freeze-thaw cycles.
  12 months from date of receipt, -20 to -70 centigrade as supplied.
  1 month, 2 to 8 centigrade under sterile conditions after reconstitution.
  3 months, -20 to -70 centigrade under sterile conditions after reconstitution.
• Storage Buffer: Lyophilized from a 0.2 μm filtered solution in PBS.
• Reconstitution: Reconstitute at 100 μg/mL in sterile PBS.

Gene Information

• Gene Name: CXADR CXADR Ig-like cell adhesion molecule [ Homo sapiens (human) ]
• Official Symbol: CXADR
• Synonyms: CXADR; CXADR Ig-like cell adhesion molecule; CAR; HCAR; CAR4/6; coxsackievirus and adenovirus receptor; 46 kD coxsackievirus and adenovirus receptor (CAR) protein; CVB3-binding protein; HCVADR; coxsackie virus and adenovirus receptor; coxsackievirus B-ade
• Gene ID: 1525
• mRNA Refseq: NM_001338
• Protein Refseq: NP_001329
• MIM: 602621
• UniProt ID: P78310