Recombinant Human CXADR Protein, Fc-tagged
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|Product Overview :||Recombinant human CXADR (Leu20 - Gly237) protein with a human IgG1 (Pro100 - Lys330) Fc tag at C-terminus was expressed in mouse myeloma cell line. Disulfide-linked homodimer.|
|Description :||The protein encoded by this gene is a type I membrane receptor for group B coxsackieviruses and subgroup C adenoviruses. Several transcript variants encoding different isoforms have been found for this gene. Pseudogenes of this gene are found on chromosomes 15, 18, and 21.|
|Source :||Mammalian cells|
|Predicted N Terminal :||Leu20|
|Bio-activity :||Measured by the ability of the immobilized protein to support the adhesion of human monocyte-derived dendritic cells. When 5 x 10^4 cells/well are added to rhCXADR/Fc Chimera coated plates (10 µg/mL), approximately 25%‑45% will adhere after 30 minutes of|
|Molecular Mass :||60-65 kDa, reducing conditions|
|Endotoxin :||<0.10 EU per 1 μg of the protein by the LAL method.|
|Purity :||>95%, by SDS-PAGE under reducing conditions and visualized by silver stain.|
|Storage :||Avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70 centigrade as supplied.
1 month, 2 to 8 centigrade under sterile conditions after reconstitution.
3 months, -20 to -70 centigrade under sterile conditions after reconstitution.
|Storage Buffer :||Lyophilized from a 0.2 μm filtered solution in PBS.|
|Reconstitution :||Reconstitute at 100 μg/mL in sterile PBS.|
|Gene Name :||CXADR CXADR Ig-like cell adhesion molecule [ Homo sapiens (human) ]|
|Official Symbol :||CXADR|
|Synonyms :||CXADR; CXADR Ig-like cell adhesion molecule; CAR; HCAR; CAR4/6; coxsackievirus and adenovirus receptor; 46 kD coxsackievirus and adenovirus receptor (CAR) protein; CVB3-binding protein; HCVADR; coxsackie virus and adenovirus receptor; coxsackievirus B-ade|
|Gene ID :||1525|
|mRNA Refseq :||NM_001338|
|Protein Refseq :||NP_001329|
|UniProt ID :||P78310|
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