Recombinant Human CXCL1 Protein, His-SUMO-tagged

• Cat.No.: CXCL1-982H
• Product Overview: Recombinant mature form of human CXCL1 (P09341-1) (Ala 35-Asn 107) was expressed in E. coli with a N-terminal polyhistide tag and SUMO tag.

Specification

• Source: E. coli
• Species: Human
• Tag: His&SUMO
• Form: Lyophilized Powder
• Molecular Mass: The recombinant human CXCL1 consisting of 189 amino acids and has a calculated molecular mass of 21.3 kDa. It migrates as an 30 kDa band in SDS-PAGE under reducing conditions.
• Purity: > 97 % as determined by SDS-PAGE
• Storage: Store it under sterile conditions at -20 centigrade to -80 centigrade. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
• Storage buffer: PBS, pH 7.4

Gene Information

• Gene Name: CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) [ Homo sapiens ]
• Official Symbol: CXCL1
• Synonyms: CXCL1; chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha); fibroblast secretory protein , FSP, GRO1, GRO1 oncogene (melanoma growth stimulating activity, alpha) , MGSA; growth-regulated alpha protein; GROa; MGSA a; NAP 3; SCYB1; MGSA alpha; GRO-alpha(1-73); C-X-C motif chemokine 1; fibroblast secretory protein; neutrophil-activating protein 3; melanoma growth stimulatory activity alpha; GRO1 oncogene (melanoma growth-stimulating activity); GRO1 oncogene (melanoma growth stimulating activity, alpha); FSP; GRO1; MGSA; NAP-3; MGSA-a
• Gene ID: 2919
• mRNA Refseq: NM_001511
• Protein Refseq: NP_001502
• MIM: 155730
• UniProt ID: P09341

Reviews

06/15/2020

Efficient delivery, great service.

01/01/2019

Product as described, perfect.

10/13/2018

Reliable for protein work.

Q&As

Are there any therapeutic strategies targeting CXCL1?

Therapeutic strategies targeting CXCL1 aim to modulate its activity in diseases like cancer and chronic inflammation.

How does CXCL1 contribute to inflammation?

It mediates inflammation by promoting leukocyte migration and activation.

What role does CXCL1 play in tumor progression?

In cancer, CXCL1 can promote tumor growth, metastasis, and angiogenesis.

What is the relationship between CXCL1 and angiogenesis?

CXCL1 contributes to angiogenesis, supporting new blood vessel formation.

What is the primary function of CXCL1 in the immune system?

CXCL1 is a chemokine that attracts neutrophils to sites of infection or injury.

In which pathological conditions is CXCL1 found to be elevated?

CXCL1 levels are elevated in conditions like cancer, inflammatory diseases, and infections.

How is the expression of CXCL1 regulated in cells?

CXCL1 expression is regulated by various stimuli, including cytokines and growth factors.