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Recombinant Human CXCL9 Protein, His-tagged

Cat.No. : CXCL9-113H
Product Overview : Recombinant Human C-X-C Motif Chemokine 9 is produced by our Mammalian expression system and the target gene encoding Thr23-Thr125 is expressed with a 6His tag at the C-terminus.
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Description : Chemokine (C-X-C Motif) Ligand 9 (CXCL9) belongs to the intercrine alpha (chemokine CXC) family. It is secreted by interferon stimulated monocytes, macrophages and endothelial cells, which elicits chemotactic functions by interacting with the chemokine receptor CXCR3. CXCL9 acts as a Th1 (type 1 helper T) cell chemoattractant and plays a role in the growth, activation and movement of cells associated with immune and inflammatory responses, and in tumour growth inhibition. It is closely related to two other CXC chemokines called CXCL10 and CXCL11, whose genes are located near the gene for CXCL9 on human chromosome 4.
Source : Human Cells
Species : Human
Tag : His
Form : Lyophilized from a 0.2 um filtered solution of 20mM PB, 150mM NaCl, pH 7.2.
Molecular Mass : Predicted Molecular Weight: 12.76kDa
Apparent Molecular Weight: 16-18kDa, reducing conditions.
AA Sequence : Thr23-Thr125
Endotoxin : Less than 0.1 ng/ug (1 EU/ug).
Purity : >95%
Storage : Lyophilized protein should be stored at < -20 centigrade, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7 centigrade for 2-7 days.
Aliquots of reconstituted samples are stable at < -20 centigrade for 3 months.
Reconstitution : Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
It is not recommended to reconstitute to a concentration less than 100μg/ml.
Dissolve the lyophilized protein in distilled water.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
Quality Statement : Purity: Greater than 95% as determined by reducing SDS-PAGE.
Shipping : The product is shipped at ambient temperature.
Upon receipt, store it immediately at the temperature listed below.
Gene Name : CXCL9 C-X-C motif chemokine ligand 9 [ Homo sapiens (human) ]
Official Symbol : CXCL9
Synonyms : C-X-C Motif Chemokine 9; Gamma-Interferon-Induced Monokine; Monokine Induced by Interferon-Gamma; HuMIG; Small-Inducible Cytokine B9; CMK; MIG; SCYB9; Humig; crg-10
Gene ID : 4283
mRNA Refseq : NM_002416.3
Protein Refseq : NP_002407.1
MIM : 601704
UniProt ID : Q07325

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (5)

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What is the relationship between CXCL9 and the chemokine receptor CXCR3? 08/16/2022

CXCL9 can bind specifically to CXCR3 and accumulate at sites of inflammation, thereby inducing and exacerbating the inflammatory response.

Do you offer CXCL9 fused with other tags? 01/25/2022

Yes, we will provide you with the most suitable labels according to your experimental needs.

Can CXCL9 be detected in lymphoid tissue under normal physiological conditions? 11/23/2020

No, CXCL9 can only be detected when the organism is inflamed or infected.

CXCL9 is secreted by which cells? 11/21/2020

CXCL9 is mainly secreted by endothelial cells and monocytes.

What diseases has CXCL9 been closely associated with the study of? 10/19/2020

CXCL9 has been linked to pulmonary embolism, asthma and breast cancer research.

Customer Reviews (2)

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Reviews
02/21/2023

    Customer service promptly feedback my requests, technical staff timely solve the problems that arise.

    04/01/2022

      The protein composition was stable and the concentration was high, which allowed me to obtain satisfactory experimental results.

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