Recombinant Human cyclin-dependent kinase 3, His-tagged

• Cat.No.: CDK3-215H
• Product Overview: CDK3, 1-305aa, Human, His tag, E.coli

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Protein Length: 1-305 a.a.
• Description: CDK3 is a member of the cyclin-dependent protein kinase family. The protein promotes entry into S phase, in part by activating members of the E2F family of transcription factors. The protein also associates with cyclin C and phosphorylates the retinoblastoma 1 protein to promote exit from G0. Recombinant human CDK3 protein, fused to His-tag at N-terminus, was expressed in E.coli.
• Form: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 1M Urea, 10% glycerol
• Molecular Mass: 37.4kDa (328aa)
• AA Sequence: MGSSHHHHHH SSGLVPRGSH MGSMDMFQKV EKIGEGTYGV VYKAKNRETG QLVALKKIRL DLEMEGVPST AIREISLLKE LKHPNIVRLL DVVHNERKLY LVFEFLSQDL KKYMDSTPGS ELPLHLIKSY LFQLLQGVSF CHSHRVIHRD LKPQNLLINE LGAIKLADFG LARAFGVPLR TYTHEVVTLW YRAPEILLGS KFYTTAVDIW SIGCIFAEMV TRKALFPGDS EIDQLFRIFR MLGTPSEDTW PGVTQLPDYK GSFPKWTRKG LEEIVPNLEP EGRDLLMQLL QYDPSQRITA KTALAHPYFS SPEPSPAARQ YVLQRFRH
• Purity: >85% by SDS - PAGE
• Storage: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
• Concentration: 0.25 mg/ml (determined by Bradford assay)

Gene Information

• Gene Name: CDK3 cyclin-dependent kinase 3 [ Homo sapiens ]
• Official Symbol: CDK3
• Synonyms: CDK3; cyclin-dependent kinase 3; cell division protein kinase 3
• Gene ID: 1018
• mRNA Refseq: NM_001258
• Protein Refseq: NP_001249
• MIM: 123828
• UniProt ID: Q00526
• Chromosome Location: 17q22-qter
• Function: ATP binding; cyclin-dependent protein kinase activity; nucleotide binding