Recombinant Human CYP2A7 Protein, GST-tagged

• Cat.No.: CYP2A7-2259H
• Product Overview: Human CYP2A7 full-length ORF ( NP_000755.2, 1 a.a. - 494 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum; its substrate has not yet been determined. This gene, which produces two transcript variants, is part of a large cluster of cytochrome P450 genes from the CYP2A, CYP2B and CYP2F subfamilies on chromosome 19q. [provided by RefSeq, Jul 2008]
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 82.8 kDa
• AA Sequence: MLASGLLLVALLACLTVMVLMSVWQ QRKSRGKLPPGPTPLPFIGNYLQLN TEHICDSIMKFSECYGPVFTIHLGP RRVVVLCGHDAVREALVDQAEEFSG RGEQATFDWVFKGYGVAFSNGERAK QLLRFAIATLRDFGVGKRGIEERIQ EESGFLIEAIRSTHGANIDPTFFLS RTVSNVISSIVFGDRFDYEDKEFLS LLSMMLGIFQFTSTSTGQLYEMFSS VMKHLPGPQQQAFKLLQGLEDFIAK KVEHNQRTLDPNSPQDFIDSFLIHM QEEEKNPNTEFYLKNLMMSTLNLFI AGTETVSTTLRYGFLLLMKHPEVEA KVHEEIDRVIGKNRQPKFEDRTKMP YMEAVIHEIQRFGDVIPMSLARRVK KDTKFRDFFLPKGTEVFPMLGSVLR DPSFFSNPQDFNPQHFLDDKGQFKK SDAFVPFSIGKRNCFGEGLARMELF LFFTTVMQNFRLKSSQSPKDIDVSP KHVVFATIPRNYTMSFLPR
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: CYP2A7 cytochrome P450, family 2, subfamily A, polypeptide 7 [ Homo sapiens ]
• Official Symbol: CYP2A7
• Synonyms: CYP2A7; cytochrome P450, family 2, subfamily A, polypeptide 7; cytochrome P450, subfamily IIA (phenobarbital inducible), polypeptide 7; cytochrome P450 2A7; CYP2A; cytochrome P450 IIA4; cytochrome P450, subfamily IIA (phenobarbital-inducible), polypeptide 7; CPA7; CPAD; CYPIIA7; P450-IIA4
• Gene ID: 1549
• mRNA Refseq: NM_000764
• Protein Refseq: NP_000755
• MIM: 608054
• UniProt ID: P20853