Recombinant Human CYP2C19/NADPH protein, Active
Cat.No. : | CYP2C19-362H |
Product Overview : | This is a permeabilized and stabilized dried yeast powder preparation containing recombinant human CYP2C19 and recombinant human P450 NADPH oxidoreductase co expressed in the same preparation. |
- Specification
- Gene Information
- Related Products
Source : | Pichia pastoris |
Species : | Human |
Form : | Lyophilized powder |
Molecular Mass : | 55 Kda |
Notes : | Centrifuge the vial prior to opening |
Storage : | Stable for 1 year as supplied. Store dry powder at -20 centigrade. Reconstitute in 50 mM Potassium Phosphate buffer, pH 7.7. Not recommended to be stored as solution. If storing as solution, aliquot and store at -80 centigrade. Avoid repeated freeze/thaw cycles and use aliquots within one month (the human CYP2C19 will lose approximately 10% activity per week when stored at -80 centigrade). Thaw aliquots rapidly at 37 centigrade and place on ice until use (thawed aliquots should be used within 4 hours). |
Reconstitution : | 50 mM Potassium Phosphate buffer, pH 7.7 |
Gene Name : | CYP2C19 cytochrome P450, family 2, subfamily C, polypeptide 19 [ Homo sapiens ] |
Official Symbol : | CYP2C19 |
Synonyms : | CYP2C19; cytochrome P450, family 2, subfamily C, polypeptide 19; CYP2C, cytochrome P450, subfamily IIC (mephenytoin 4 hydroxylase), polypeptide 19; cytochrome P450 2C19; CPCJ; P450IIC19; CYPIIC17; CYPIIC19; cytochrome P450-11A; cytochrome P450-254C; cytochrome P-450 II C; microsomal monooxygenase; xenobiotic monooxygenase; mephenytoin 4-hydroxylase; S-mephenytoin 4-hydroxylase; (R)-limonene 6-monooxygenase; (S)-limonene 6-monooxygenase; (S)-limonene 7-monooxygenase; flavoprotein-linked monooxygenase; cytochrome P450, subfamily IIC (mephenytoin 4-hydroxylase), polypeptide 19; CYP2C; P450C2C; |
Gene ID : | 1557 |
mRNA Refseq : | NM_000769 |
Protein Refseq : | NP_000760 |
MIM : | 124020 |
UniProt ID : | P33261 |
Chromosome Location : | 10q24 |
Pathway : | Arachidonic acid metabolism, organism-specific biosystem; Arachidonic acid metabolism, conserved biosystem; Biological oxidations, organism-specific biosystem; Cytochrome P450 - arranged by substrate type, organism-specific biosystem; Drug metabolism - cytochrome P450, organism-specific biosystem; Drug metabolism - cytochrome P450, conserved biosystem; Linoleic acid metabolism, organism-specific biosystem; |
Function : | (R)-limonene 6-monooxygenase activity; (S)-limonene 6-monooxygenase activity; (S)-limonene 7-monooxygenase activity; electron carrier activity; enzyme binding; heme binding; metal ion binding; monooxygenase activity; oxidoreductase activity; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; oxygen binding; steroid hydroxylase activity; |
Products Types
◆ Recombinant Protein | ||
CYP2C19-2726H | Recombinant Human CYP2C19 protein(251-320 aa), C-His-tagged | +Inquiry |
CYP2C19-75H | Active Recombinant Human CYP2C19 Protein | +Inquiry |
CYP2C19-126C | Active Recombinant Cynomolgus CYP2C19 Protein | +Inquiry |
CYP2C19-33H | Active Recombinant Human CYP2C19 Protein | +Inquiry |
CYP2C19-2797H | Recombinant Human CYP2C19 Protein, His-tagged, OVA Conjugated | +Inquiry |
◆ Assay kits | ||
Kit-2125 | Cytochrome P450 2C19 Inhibitor Screening Kit | +Inquiry |
Kit-2124 | Cytochrome P450 2C19 Fluorometric Activity Assay Kit | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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