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Recombinant Human DAAM1 Protein, GST-tagged

Cat.No. : DAAM1-2312H
Product Overview : Human DAAM1 partial ORF ( NP_055807, 1 a.a. - 110 a.a.) recombinant protein with GST-tag at N-terminal.
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  • Gene Information
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Description : Cell motility, adhesion, cytokinesis, and other functions of the cell cortex are mediated by reorganization of the actin cytoskeleton and several formin homology (FH) proteins have been associated with these processes. The protein encoded by this gene contains two FH domains and belongs to a novel FH protein subfamily implicated in cell polarity. A key regulator of cytoskeletal architecture, the small GTPase Rho, is activated during development by Wnt/Fz signaling to control cell polarity and movement. The protein encoded by this gene is thought to function as a scaffolding protein for the Wnt-induced assembly of a disheveled (Dvl)-Rho complex. This protein also promotes the nucleation and elongation of new actin filaments and regulates cell growth through the stabilization of microtubules. Alternative splicing results in multiple transcript variants encoding distinct proteins. [provided by RefSeq, Jul 2012]
Source : Wheat Germ
Species : Human
Tag : GST
Molecular Mass : 37.84 kDa
AA Sequence : MAPRKRGGRGISFIFCCFRNNDHPE ITYRLRNDSNFALQTMEPALPMPPV EELDVMFSELVDELDLTDKHREAMF ALPAEKKWQIYCSKKKDQEENKGAT SWPEFYIDQL
Applications : Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
Notes : Best use within three months from the date of receipt of this protein.
Storage : Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
Storage Buffer : 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Gene Name : DAAM1 dishevelled associated activator of morphogenesis 1 [ Homo sapiens ]
Official Symbol : DAAM1
Synonyms : DAAM1; dishevelled associated activator of morphogenesis 1; disheveled-associated activator of morphogenesis 1; KIAA0666; FLJ41657;
Gene ID : 23002
mRNA Refseq : NM_014992
Protein Refseq : NP_055807
MIM : 606626
UniProt ID : Q9Y4D1

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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