| Description : |
The laminar organization of multiple neuronal types in the cerebral cortex is required for normal cognitive function. In mice, the disabled-1 gene plays a central role in brain development, directing the migration of cortical neurons past previously formed neurons to reach their proper layer. This gene is similar to disabled-1, and the protein encoded by this gene is thought to be a signal transducer that interacts with protein kinase pathways to regulate neuronal positioning in the developing brain. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Myc/DDK |
| Molecular Mass : |
59.8 kDa |
| AA Sequence : |
MSTETELQVAVKTSAKKDSRKKGQD RSEATLIKRFKGEGVRYKAKLIGID EVSAARGDKLCQDSMMKLKGVVAGA RSKGEHKQKIFLTISFGGIKIFDEK TGALQHHHAVHEISYIAKDITDHRA FGYVCGKEGNHRFVAIKTAQAAEPV ILDLRDLFQLIYELKQREELEKKAQ KDKQCEQAVYQTILEEDVEDPVYQY IVFEAGHEPIRDPETEENIYQVPTS QKKEGVYDVPKSQPVSAVTQLELFG DMSTPPDITSPPTPATPGDAFIPSS SQTLPASADVFSSVPFGTAAVPSGY VAMGAVLPSFWGQQPLVQQQMVMGA QPPVAQVMPGAQPIAWGQPGLFPAT QQPWPTVAGQFPPAAFMPTQTVMPL PAAMFQGPLTPLATVPGTSDSTRSS PQTDKPRQKMGKETFKDFQMAQPPP VPSRKPDQPSLTCTSEAFSSYFNKV GVAQDTDDCDDFDISQLNLTPVTST TPSTNSPPTPAPRQSSPSKSSASHA SDPTTDDIFEEGFESPSKSEEQEAP DGSQASSNSDPFGEPSGEPSGDNIS PQAGSTRTRPLEQKLISEEDLAAND ILDYKDDDDKV |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : |
50 μg/mL as determined by BCA |
| Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
