Recombinant Human DAB1 Protein, GST-tagged

• Cat.No.: DAB1-2314H
• Product Overview: Human DAB1 full-length ORF ( AAH67445.1, 1 a.a. - 553 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: The laminar organization of multiple neuronal types in the cerebral cortex is required for normal cognitive function. In mice, the disabled-1 gene plays a central role in brain development, directing the migration of cortical neurons past previously formed neurons to reach their proper layer. This gene is similar to disabled-1, and the protein encoded by this gene is thought to be a signal transducer that interacts with protein kinase pathways to regulate neuronal positioning in the developing brain. [provided by RefSeq, Jan 2017]
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 86 kDa
• AA Sequence: MSTETELQVAVKTSAKKDSRKKGQD RSEATLIKRFKGEGVRYKAKLIGID EVSAARGDKLCQDSMMKLKGVVAGA RSKGEHKQKIFLTISFGGIKIFDEK TGALQHHHAVHEISYIAKDITDHRA FGYVCGKEGNHRFVAIKTAQAAEPV ILDLRDLFQLIYELKQREELEKKAQ KDKQCEQAVYQVPTSQKKEGVYDVP KSQPVSNGYSFEDFEERFAAATPNR NLPTDFDEIFEATKAVTQLELFGDM STPPDITSPPTPATPGDAFIPSSSQ TLPASADVFSSVPFGTAAVPSGYVA MGAVLPSFWGQQPLVQQQMVMGAQP PVAQVMPGAQPIAWGQPGLFPATQQ PWPTVAGQFPPAAFMPTQTVMPLPA AMFQGPLTPLATVPGTSDSTRSSPQ TDKPRQKMGKETFKDFQMAQPPPVP SRKPDQPSLTCTSEAFSSYFNKVGV AQDTDDCDDFDISQLNLTPVTSTTP STNSPPTPAPRQSSPSKSSASHASD PTTDDIFEEGFESPSKSEEQEAPDG SQASSNSDPFGEPSGEPSGDNISPQ AGS
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: DAB1 disabled homolog 1 (Drosophila) [ Homo sapiens ]
• Official Symbol: DAB1
• Synonyms: DAB1; disabled homolog 1 (Drosophila); disabled (Drosophila) homolog 1; disabled homolog 1
• Gene ID: 1600
• mRNA Refseq: NM_021080
• Protein Refseq: NP_066566
• MIM: 603448
• UniProt ID: O75553