Recombinant Human DARS2 Protein, GST-tagged

• Cat.No.: DARS2-2350H
• Product Overview: Human DARS2 full-length ORF ( NP_060592.2, 1 a.a. - 645 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: The protein encoded by this gene belongs to the class-II aminoacyl-tRNA synthetase family. It is a mitochondrial enzyme that specifically aminoacylates aspartyl-tRNA. Mutations in this gene are associated with leukoencephalopathy with brainstem and spinal cord involvement and lactate elevation (LBSL). [provided by RefSeq, Nov 2009]
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 100 kDa
• AA Sequence: MYFPSWLSQLYRGLSRPIRRTTQPI WGSLYRSLLQSSQRRIPEFSSFVVR TNTCGELRSSHLGQEVTLCGWIQYR RQNTFLVLRDFDGLVQVIIPQDESA ASVKKILCEAPVESVVQVSGTVISR PAGQENPKMPTGEIEIKVKTAELLN ACKKLPFEIKNFVKKTEALRLQYRY LDLRSFQMQYNLRLRSQMVMKMREY LCNLHGFVDIETPTLFKRTPGGAKE FLVPSREPGKFYSLPQSPQQFKQLL MVGGLDRYFQVARCYRDEGSRPDRQ PEFTQIDIEMSFVDQTGIQSLIEGL LQYSWPNDKDPVVVPFPTMTFAEVL ATYGTDKPDTRFGMKIIDISDVFRN TEIGFLQDALSKPHGTVKAICIPEG AKYLKRKDIESIRNFAADHFNQEIL PVFLNANRNWNSPVANFIMESQRLE LIRLMETQEEDVVLLTAGEHNKACS LLGKLRLECADLLETRGVVLRDPTL FSFLWVVDFPLFLPKEENPRELESA HHPFTAPHPSDIHLLYTEPKKARSQ HYDLVLNGNEIGGGSIRIHNAELQR YILATLLKEDVKMLSHLLQALDYGA PPHGGIALGLDRLICLVTGSPSIRD VIAFPKSFRGHDLMSNTPDSVPPEE LKPYHIRVSKPTDSKAERAH
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: DARS2 aspartyl-tRNA synthetase 2, mitochondrial [ Homo sapiens ]
• Official Symbol: DARS2
• Synonyms: DARS2; aspartyl-tRNA synthetase 2, mitochondrial; aspartate--tRNA ligase, mitochondrial; aspartate tRNA ligase 2; mitochondrial; FLJ10514; aspartate tRNA ligase 2, mitochondrial; aspartyl-tRNA synthetase, mitochondrial; LBSL; ASPRS; MT-ASPRS; RP3-383J4.2
• Gene ID: 55157
• mRNA Refseq: NM_018122
• Protein Refseq: NP_060592
• MIM: 610956
• UniProt ID: Q6PI48