Recombinant Human DDC Protein, Myc/DDK-tagged, C13 and N15-labeled
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| Cat.No. : | DDC-3118H |
| Product Overview : | DDC MS Standard C13 and N15-labeled recombinant protein (NP_000781) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells. |
| Description : | The encoded protein catalyzes the decarboxylation of L-3,4-dihydroxyphenylalanine (DOPA) to dopamine, L-5-hydroxytryptophan to serotonin and L-tryptophan to tryptamine. Defects in this gene are the cause of aromatic L-amino-acid decarboxylase deficiency (AADCD). AADCD deficiency is an inborn error in neurotransmitter metabolism that leads to combined serotonin and catecholamine deficiency. Multiple alternatively spliced transcript variants encoding different isoforms have been identified for this gene. |
| Source : | HEK293 |
| Species : | Human |
| Tag : | Myc/DDK |
| Molecular Mass : | 53.9 kDa |
| AA Sequence : | MNASEFRRRG KEMVDYVANY MEGIEGRQVY PDVEPGYLRP LIPAAAPQEP DTFEDIINDV EKIIMPGVTH WHSPYFFAYF PTASSYPAML ADMLCGAIGC IGFSWAASPA CTELETVMMD WLGKMLELPK AFLNEKAGEG GGVIQGSASE ATLVALLAAR TKVIHRLQAA SPELTQAAIM EKLVAYSSDQ AHSSVERAGL IGGVKLKAIP SDGNFAMRAS ALQEALERDK AAGLIPFFMV ATLGTTTCCS FDNLLEVGPI CNKEDIWLHV DAAYAGSAFI CPEFRHLLNG VEFADSFNFN PHKWLLVNFD CSAMWVKKRT DLTGAFRLDP TYLKHSHQDS GLITDYRHWQ IPLGRRFRSL KMWFVFRMYG VKGLQAYIRK HVQLSHEFES LVRQDPRFEI CVEVILGLVC FRLKGSNKVN EALLQRINSA KKIHLVPCHL RDKFVLRFAI CSRTVESAHV QRAWEHIKEL AADVLRAERE TRTRPLEQKL ISEEDLAAND ILDYKDDDDK V |
| Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : | Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : | Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : | 50 μg/mL as determined by BCA |
| Storage Buffer : | 100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
| SDS-PAGE : |
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| Gene Name : | DDC dopa decarboxylase [ Homo sapiens (human) ] |
| Official Symbol : | DDC |
| Synonyms : | DDC; dopa decarboxylase (aromatic L-amino acid decarboxylase); aromatic-L-amino-acid decarboxylase; AADC; |
| Gene ID : | 1644 |
| mRNA Refseq : | NM_000790 |
| Protein Refseq : | NP_000781 |
| MIM : | 107930 |
| UniProt ID : | P20711 |
◆ Recombinant Protein
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| Ddc-2490M | Recombinant Mouse Ddc Protein, Myc/DDK-tagged | +Inquiry |
| DDC-491H | Recombinant Human DDC Protein, His-tagged | +Inquiry |
| DDC-284H | Recombinant Human DDC, His tagged | +Inquiry |
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◆ Lysates
| DDC-724HCL | Recombinant Human DDC cell lysate | +Inquiry |
| DDC-513MCL | Recombinant Mouse DDC cell lysate | +Inquiry |
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