Recombinant Human DDX18 Protein, GST-tagged

• Cat.No.: DDX18-2466H
• Product Overview: Human DDX18 full-length ORF (BAA91709.1, 1 a.a. - 670 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein, and it is activated by Myc protein. [provided by RefSeq, Jul 2008]
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 101.8 kDa
• AA Sequence: MSHLPMKLLRKKIEKRNLKLRQRNL KFQGASNLTLSETQNGDVSEETMGS RKVKKSKQKPMNVGLSETQNGGMSQ EAVGNIKVTKSPQKSTVLTNGEAAM QSSNSESKKKKKKKRKMVNDAEPDT KKAKTENKGKSEEESAETTKETENN VEKPDNDEDESEVPSLPLGLTGAFE DTSFASLCNLVNENTLKAIKEMGFT NMTEIQHKSIRPLLEGRDLLAAAKT GSGKTLAFLIPAVELIVKLRFMTRN GTGVLILSPTRELAMQTFGVLKELM THHVHTYGLIMGGSNRSAEAQKLGN GINIIVATPGRLLDHMQNTPGFMYK NLQCLVIDEADRILDVGFEEELKQI IKLLPTRRQTMLFSATQTRKVEDLA RISLKKEPLYVGVDDDKANATVDGL EQGYVVCPSEKRFLLLFTFLKKNRK KKLMVFFSSCMSVKYHYELLNYIDL PVLAIHGKQKQNKRTTTFFQFCNAD SGTLLCTDVAARGLDIPEVDWIVQY DPPDDPKEYIHRVGRTARGLNGRGH ALLILRPEELGFLRYLKQSKVPLSE FDFSWSKISDIQSQLEKLIEKNYFL HKSAQEAYKSYIRAYDSHSLKQIFN VNNLNLPQVALSFGFKVPPFVDLNV NSNEGKQKKRGGGGGFGYQKTKKVE KSKIFKHISKKSSDSRQFSH
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: DDX18 DEAD (Asp-Glu-Ala-Asp) box polypeptide 18 [ Homo sapiens ]
• Official Symbol: DDX18
• Synonyms: DDX18; DEAD (Asp-Glu-Ala-Asp) box polypeptide 18; DEAD/H (Asp Glu Ala Asp/His) box polypeptide 18 (Myc regulated); ATP-dependent RNA helicase DDX18; MrDb; DEAD box protein 18; Myc-regulated DEAD box protein; DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 18 (Myc-regulated); FLJ33908
• Gene ID: 8886
• mRNA Refseq: NM_006773
• Protein Refseq: NP_006764
• MIM: 606355
• UniProt ID: Q9NVP1