Recombinant Human DHCR24 Protein, Myc/DDK-tagged, C13 and N15-labeled
Cat.No. : | DHCR24-5686H |
Product Overview : | DHCR24 MS Standard C13 and N15-labeled recombinant protein (NP_055577) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes a flavin adenine dinucleotide (FAD)-dependent oxidoreductase which catalyzes the reduction of the delta-24 double bond of sterol intermediates during cholesterol biosynthesis. The protein contains a leader sequence that directs it to the endoplasmic reticulum membrane. Missense mutations in this gene have been associated with desmosterolosis. Also, reduced expression of the gene occurs in the temporal cortex of Alzheimer disease patients and overexpression has been observed in adrenal gland cancer cells. |
Source : | HEK293 |
Species : | Human |
Tag : | Myc/DDK |
Molecular Mass : | 60.1 kDa |
AA Sequence : | MEPAVSLAVCALLFLLWVRLKGLEF VLIHQRWVFVCLFLLPLSLIFDIYY YVRAWVVFKLSSAPRLHEQRVRDIQ KQVREWKEQGSKTFMCTGRPGWLTV SLRVGKYKKTHKNIMINLMDILEVD TKKQIVRVEPLVTMGQVTALLTSIG WTLPVLPELDDLTVGGLIMGTGIES SSHKYGLFQHICTAYELVLADGSFV RCTPSENSDLFYAVPWSCGTLGFLV AAEIRIIPAKKYVKLRFEPVRGLEA ICAKFTHESQRQENHFVEGLLYSLD EAVIMTGVMTDEAEPSKLNSIGNYY KPWFFKHVENYLKTNREGLEYIPLR HYYHRHTRSIFWELQDIIPFGNNPI FRYLFGWMVPPKISLLKLTQGETLR KLYEQHHVVQDMLVPMKCLQQALHT FQNDIHVYPIWLCPFILPSQPGLVH PKGNEAELYIDIGAYGEPRVKHFEA RSCMRQLEKFVRSVHGFQMLYADCY MNREEFWEMFDGSLYHKLREKLGCQ DAFPEVYDKICKAARHTRTRPLEQK LISEEDLAANDILDYKDDDDKV |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Stability : | Stable for 3 months from receipt of products under proper storage and handling conditions. |
Storage : | Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
Concentration : | 50 μg/mL as determined by BCA |
Storage Buffer : | 100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
Gene Name : | DHCR24 24-dehydrocholesterol reductase [ Homo sapiens (human) ] |
Official Symbol : | DHCR24 |
Synonyms : | DHCR24; 24-dehydrocholesterol reductase; delta(24)-sterol reductase; KIAA0018; seladin 1; diminuto/dwarf1 homolog; selective AD indicator 1; desmosterol-to-cholesterol enzyme; 3 beta-hydroxysterol delta 24-reductase; 3-beta-hydroxysterol delta-24-reductase; DCE; SELADIN1; Nbla03646; seladin-1; |
Gene ID : | 1718 |
mRNA Refseq : | NM_014762 |
Protein Refseq : | NP_055577 |
MIM : | 606418 |
UniProt ID : | Q15392 |
Products Types
◆ Recombinant Protein | ||
Dhcr24-2542M | Recombinant Mouse Dhcr24 Protein, Myc/DDK-tagged | +Inquiry |
DHCR24-754H | Recombinant Human DHCR24 Protein, His (Fc)-Avi-tagged | +Inquiry |
DHCR24-208C | Recombinant Cynomolgus Monkey DHCR24 Protein, His (Fc)-Avi-tagged | +Inquiry |
DHCR24-1959H | Recombinant Human DHCR24 Protein (Arg53-His516), N-His tagged | +Inquiry |
DHCR24-105H | Recombinant Human DHCR24 protein, MYC/DDK-tagged | +Inquiry |
◆ Lysates | ||
DHCR24-6950HCL | Recombinant Human DHCR24 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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