| Description : |
This gene is a member of the DEAH-box family of RNA-dependent NTPases which are named after the conserved amino acid sequence Asp-Glu-Ala-His in motif II. The protein encoded by this gene has been shown to enhance the deadenylation and decay of mRNAs with 3'-UTR AU-rich elements (ARE-mRNA). The protein has also been shown to resolve into single strands the highly stable tetramolecular DNA configuration (G4) that can form spontaneously in guanine-rich regions of DNA. Alternative splicing results in multiple transcript variants encoding different isoforms. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Myc/DDK |
| Molecular Mass : |
114.6 kDa |
| AA Sequence : |
MSYDYHQNWGRDGGPRSSGGGYGGG PAGGHGGNRGSGGGGGGGGGGRGGR GRHPGHLKGREIGMWYAKKQGQKNK EAERQERAVVHMDERREEQIVQLLN SVQAKNDKESEAQISWFAPEDHGYG TEVSTKNTPCSENKLDIQEKKLINQ EKKMFRIRNRSYIDRDSEYLLQENE PDGTLDQKLLEDLQKKKNDLRYIEM QHFREKLPSYGMQKELVNLIDNHQV TVISGETGCGKTTQVTQFILDNYIE RGKGSACRIVCTQPRRISAISVAER VAAERAESCGSGNSTGYQIRLQSRL PRKQGSILYCTTGIILQWLQSDPYL SSVSHIVLDEIHERNLQSDVLMTVV KDLLNFRSDLKVILMSATLNAEKFS EYFGNCPMIHIPGFTFPVVEYLLED VIEKIRYVPEQKEHRCQFKRGFMQG HVNRQEKEEKEAIYKERWPDYVREL RRRYSASTVDVIEMMEDDKVDLNLI VALIRYIVLEEEDGAILVFLPGWDN ISTLHDLLMSQVMFKSDKFLIIPLH SLMPTVNQTQVFKRTPPGVRKIVIA TNIAETSITIDDVVYVIDGGKIKET HFDTQNNISTMSAEWVSKANAKQRK GRAGRVQPGHCYHLYNGLRASLLDD YQLPEILRTPLEELCLQIKILRLGG IAYFLSRLMDPPSNEAVLLSIRHLM ELNALDKQEELTPLGVHLARLPVEP HIGKMILFGALFCCLDPVLTIAASL SFKDPFVIPLGKEKIADARRKELAK DTRSDHLTVVNAFEGWEEARRRGFR YEKDYCWEYFLSSNTLQMLHNMKGQ FAEHLLGAGFVSSRNPKDPESNINS DNEKIIKAVICAGLYPKVAKIRLNL GKKRKMVKVYTKTDGLVAVHPKSVN VEQTDFHYNWLIYHLKMRTSSIYLY DCTEVSPYCLLFFGGDISIQKDNDQ ETIAVDEWIVFQSPARIAHLVKELR KELDILLQEKIESPHPVDWNDTKSR DCAVLSAIIDLIKTQEKATPRNFPP RFQDGYYSTRTRPLEQKLISEEDLA ANDILDYKDDDDKV |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : |
50 μg/mL as determined by BCA |
| Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
