Recombinant Human Dipeptidyl-Peptidase 3, GST-tagged

• Cat.No.: DPP3-515H
• Product Overview: Recombinant Human DPP3 (full length) was expressed in aBaculovirus infected Sf9cell expression system with N-terminal GST tag. MW=109 kDa.

Specification

• Cat. No.: DPP3-515H
• Description: Dipeptidyl-peptidase 3 is an enzyme that in humans is encoded by the DPP3 gene. This gene encodes a protein that is a member of the S9B family in clan SC of the serine proteases. This cytoplasmic protein binds a single zinc ion with its zinc-binding motif (HELLGH) and has post-proline dipeptidyl aminopeptidase activity, cleaving Xaa-Pro dipeptides from the N-termini of proteins. Increased activity of this protein is associated with endometrial and ovarian cancers. Alternate transcriptional splice variants have been characterized.
• Source: Sf9.
• Formulated In: 25 mM Tris-HCl, pH 8.0, 100 mM NaCl, 0.05% Tween-20, 50% glycerol, and 3 mM DTT.
• Application: Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling.
• Purity: > 70%.
• Stability: >6 months at -80°C.

Gene Information

• Gene Name: DPP3 dipeptidyl-peptidase 3 [ Homo sapiens ]
• Synonyms: dipeptidyl-peptidase 3; DPPIII; FLJ11387; FLJ22331; DPP3; dipeptidyl peptidase III; dipeptidylpeptidase 3; dipeptidylpeptidase III; dipeptidyl arylamidase III; dipeptidyl aminopeptidase III; EC 3.4.14.4; DPP III; Dipeptidyl aminopeptidase III; Dipeptidyl arylamidase III; Dipeptidyl-peptidase III
• Gene ID: 10072
• mRNA Refseq: NM_005700
• Protein Refseq: NP_005691
• MIM: 606818
• UniProt ID: Q9NY33
• Chromosome Location: 11q12-q13.1
• Function: aminopeptidase activity; dipeptidyl-peptidase activity; metal ion binding; metallopeptidase activity; peptidase activity; zinc ion binding