| Description : |
DIS3 (DIS3 Homolog, Exosome Endoribonuclease And 3'-5' Exoribonuclease) is a Protein Coding gene. Diseases associated with DIS3 include Perlman Syndrome and Axenfeld-Rieger Syndrome, Type 2. Among its related pathways are Regulation of activated PAK-2p34 by proteasome mediated degradation and ATP/ITP metabolism. Gene Ontology (GO) annotations related to this gene include RNA binding and endonuclease activity. An important paralog of this gene is DIS3L. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Myc/DDK |
| Molecular Mass : |
109.1 kDa |
| AA Sequence : |
MLKSKTFLKKTRAGGVMKIVREHYL RDDIGCGAPGCAACGGAHEGPALEP QPQDPASSVCPQPHYLLPDTNVLLH QIDVLEDPAIRNVIVLQTVLQEVRN RSAPVYKRIRDVTNNQEKHFYTFTN EHHRETYVEQEQGENANDRNDRAIR VAAKWYNEHLKKMSADNQLQVIFIT NDRRNKEKAIEEGIPAFTCEEYVKS LTANPELIDRLACLSEEGNEIESGK IIFSEHLPLSKLQQGIKSGTYLQGT FRASRENYLEATVWIHGDNEENKEI ILQGLKHLNRAVHEDIVAVELLPKS QWVAPSSVVLHDEGQNEEDVEKEEE RERMLKTAVSEKMLKPTGRVVGIIK RNWRPYCGMLSKSDIKESRRHLFTP ADKRIPRIRIETRQASTLEGRRIIV AIDGWPRNSRYPNGHFVRNLGDVGE KETETEVLLLEHDVPHQPFSQAVLS FLPKMPWSITEKDMKNREDLRHLCI CSVDPPGCTDIDDALHCRELENGNL EVGVHIADVSHFIRPGNALDQESAR RGTTVYLCEKRIDMVPELLSSNLCS LKCDVDRLAFSCIWEMNHNAEILKT KFTKSVINSKASLTYAEAQLRIDSA NMNDDITTSLRGLNKLAKILKKRRI EKGALTLSSPEVRFHMDSETHDPID LQTKELRETNSMVEEFMLLANISVA KKIHEEFSEHALLRKHPAPPPSNYE ILVKAARSRNLEIKTDTAKSLAESL DQAESPTFPYLNTLLRILATRCMMQ AVYFCSGMDNDFHHYGLASPIYTHF TSPIRRYADVIVHRLLAVAIGADCT YPELTDKHKLADICKNLNFRHKMAQ YAQRASVAFHTQLFFKSKGIVSEEA YILFVRKNAIVVLIPKYGLEGTVFF EEKDKPNPQLIYDDEIPSLKIEDTV FHVFDKVKVKIMLDSSNLQHQKIRM SLVEPQIPGISIPTDTSNMDLNGPK KKKMKLGKTRTRPLEQKLISEEDLA ANDILDYKDDDDKV |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : |
50 μg/mL as determined by BCA |
| Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
