Recombinant Human DIS3 Protein, Myc/DDK-tagged, C13 and N15-labeled

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Recombinant Human DIS3 Protein, Myc/DDK-tagged, C13 and N15-labeled

DIS3 Related Products

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Cat.No. : DIS3-6219H
Product Overview : DIS3 MS Standard C13 and N15-labeled recombinant protein (NP_055768) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.
Description : DIS3 (DIS3 Homolog, Exosome Endoribonuclease And 3'-5' Exoribonuclease) is a Protein Coding gene. Diseases associated with DIS3 include Perlman Syndrome and Axenfeld-Rieger Syndrome, Type 2. Among its related pathways are Regulation of activated PAK-2p34 by proteasome mediated degradation and ATP/ITP metabolism. Gene Ontology (GO) annotations related to this gene include RNA binding and endonuclease activity. An important paralog of this gene is DIS3L.
Source : HEK293
Species : Human
Tag : Myc/DDK
Molecular Mass : 109.1 kDa
AA Sequence : MLKSKTFLKK TRAGGVMKIV REHYLRDDIG CGAPGCAACG GAHEGPALEP QPQDPASSVC PQPHYLLPDT NVLLHQIDVL EDPAIRNVIV LQTVLQEVRN RSAPVYKRIR DVTNNQEKHF YTFTNEHHRE TYVEQEQGEN ANDRNDRAIR VAAKWYNEHL KKMSADNQLQ VIFITNDRRN KEKAIEEGIP AFTCEEYVKS LTANPELIDR LACLSEEGNE IESGKIIFSE HLPLSKLQQG IKSGTYLQGT FRASRENYLE ATVWIHGDNE ENKEIILQGL KHLNRAVHED IVAVELLPKS QWVAPSSVVL HDEGQNEEDV EKEEERERML KTAVSEKMLK PTGRVVGIIK RNWRPYCGML SKSDIKESRR HLFTPADKRI PRIRIETRQA STLEGRRIIV AIDGWPRNSR YPNGHFVRNL GDVGEKETET EVLLLEHDVP HQPFSQAVLS FLPKMPWSIT EKDMKNREDL RHLCICSVDP PGCTDIDDAL HCRELENGNL EVGVHIADVS HFIRPGNALD QESARRGTTV YLCEKRIDMV PELLSSNLCS LKCDVDRLAF SCIWEMNHNA EILKTKFTKS VINSKASLTY AEAQLRIDSA NMNDDITTSL RGLNKLAKIL KKRRIEKGAL TLSSPEVRFH MDSETHDPID LQTKELRETN SMVEEFMLLA NISVAKKIHE EFSEHALLRK HPAPPPSNYE ILVKAARSRN LEIKTDTAKS LAESLDQAES PTFPYLNTLL RILATRCMMQ AVYFCSGMDN DFHHYGLASP IYTHFTSPIR RYADVIVHRL LAVAIGADCT YPELTDKHKL ADICKNLNFR HKMAQYAQRA SVAFHTQLFF KSKGIVSEEA YILFVRKNAI VVLIPKYGLE GTVFFEEKDK PNPQLIYDDE IPSLKIEDTV FHVFDKVKVK IMLDSSNLQH QKIRMSLVEP QIPGISIPTD TSNMDLNGPK KKKMKLGKTR TRPLEQKLIS EEDLAANDIL DYKDDDDKV
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Stability : Stable for 3 months from receipt of products under proper storage and handling conditions.
Storage : Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
Concentration : 50 μg/mL as determined by BCA
Storage Buffer : 100 mM glycine, 25 mM Tris-HCl, pH 7.3.
SDS-PAGE :

Gene Name : DIS3 DIS3 homolog, exosome endoribonuclease and 3'-5' exoribonuclease [ Homo sapiens (human) ]
Official Symbol : DIS3
Synonyms : DIS3; DIS3 mitotic control homolog (S. cerevisiae); KIAA1008; exosome complex exonuclease RRP44; dis3p; EXOSC11; exosome component 11; RRP44; 2810028N01Rik; protein DIS3 homolog; ribosomal RNA-processing protein 44; mitotic control protein dis3 homolog; bA555G22.1; RP11-342J4.3; FLJ10484; MGC33035; DKFZp667L1817;
Gene ID : 22894
mRNA Refseq : NM_014953
Protein Refseq : NP_055768
MIM : 607533
UniProt ID : Q9Y2L1

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