Recombinant Human DIS3L2 Protein, GST-tagged

• Cat.No.: DIS3L2-2641H
• Product Overview: Human DIS3L2 full-length ORF ( NP_689596.3, 1 a.a. - 619 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: The protein encoded by this gene is similar in sequence to 3'/5' exonucleolytic subunits of the RNA exosome. The exosome is a large multimeric ribonucleotide complex responsible for degrading various RNA substrates. Several transcript variants, some protein-coding and some not, have been found for this gene. [provided by RefSeq, Mar 2012]
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 95.5 kDa
• AA Sequence: MSHPDYRMNLRSLGTHRGVSAVAGP HDIGASPGDKKSKNRSTRGKKKSIF ETYMSKEDVSEGLKRGTLIQGVLRI NPKKFHEAFIPSPDGDRDIFIDGVV ARNRALNGDLVVVKLLPEEHWKVVK PESNDKETEAAYESDIPEELCGHHL PQQSLKSYNDSPDVIVEAQFDGSDS EDGHGITQNVLVDGVKKLSVCVSEK GREDGDAPVTKDETTCISQDTRALS EKSLQRSAKVVYILEKKHSRAATGF LKLLADKNSELFRKYALFSPSDHRV PRIYVPLKDCPQDFVARPKDYANTL FICRIVDWKEDCNFALGQLAKSLGQ AGEIEPETEGILTEYGVDFSDFSSE VLECLPQGLPWTIPPEEFSKRRDLR KDCIFTIDPSTARDLDDALSCKPLA DGNFKVGVHIADVSYFVPEGSDLDK VAAERATSVYLVQKVVPMLPRLLCE ELCSLNPMSDKLTFSVIWTLTPEGK ILDEWFGRTIIRSCTKLSYEHAQSM IESPTEKIPAKELPPISPEHSSEEV HQAVLNLHGIAKQLRQQRFVDGALR LDQLKLAFTLDHETGLPQGCHIYEY RESNKPCCAGTPRPKQGCSVTWWNS ATRWGCPWTSAPQEPSIKA
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: DIS3L2 DIS3 mitotic control homolog (S. cerevisiae)-like 2 [ Homo sapiens ]
• Official Symbol: DIS3L2
• Synonyms: DIS3L2; DIS3 mitotic control homolog (S. cerevisiae)-like 2; FAM6A, family with sequence similarity 6, member A; DIS3-like exonuclease 2; FLJ36974; MGC42174; family with sequence similarity 6, member A; FAM6A; PRLMNS
• Gene ID: 129563
• mRNA Refseq: NM_001257281
• Protein Refseq: NP_001244210
• MIM: 614184
• UniProt ID: Q8IYB7