Recombinant Human DMP1 Protein, MYC/DDK-tagged
Cat.No. : | DMP1-2212H |
Product Overview : | Recombinant human DMP1 protein, fused to MYC/DDK-tagged at C-terminus, was expressed in HEK293 |
- Specification
- Gene Information
- Related Products
Description : | Dentin matrix acidic phosphoprotein is an extracellular matrix protein and a member of the small integrin binding ligand N-linked glycoprotein family. This protein, which is critical for proper mineralization of bone and dentin, is present in diverse cells of bone and tooth tissues. The protein contains a large number of acidic domains, multiple phosphorylation sites, a functional arg-gly-asp cell attachment sequence, and a DNA binding domain. In undifferentiated osteoblasts it is primarily a nuclear protein that regulates the expression of osteoblast-specific genes. During osteoblast maturation the protein becomes phosphorylated and is exported to the extracellular matrix, where it orchestrates mineralized matrix formation. Mutations in the gene are known to cause autosomal recessive hypophosphatemia, a disease that manifests as rickets and osteomalacia. The gene structure is conserved in mammals. Two transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008] |
Source : | HEK293 |
Species : | Human |
Tag : | MYC/DDK |
Form : | 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
Molecular Mass : | 52.3 kDa |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Concentration : | >50 ug/mL as determined by microplate BCA method |
Gene Name : | DMP1 dentin matrix acidic phosphoprotein 1 [ Homo sapiens ] |
Official Symbol : | DMP1 |
Synonyms : | ARHP; ARHR; DMP-1 |
Gene ID : | 1758 |
mRNA Refseq : | NM_001079911 |
Protein Refseq : | NP_001073380 |
MIM : | 600980 |
UniProt ID : | Q13316 |
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◆ Lysates | ||
DMP1-1977HCL | Recombinant Human DMP1 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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