Recombinant Human DMRT1

Species :	Human
Source :	Wheat Germ
Tag :	Non
Protein Length :	373 amino acids
Description :	This gene is found in a cluster with two other members of the gene family, having in common a zinc finger-like DNA-binding motif (DM domain). The DM domain is an ancient, conserved component of the vertebrate sex-determining pathway that is also a key regulator of male development in flies and nematodes. This gene exhibits a gonad-specific and sexually dimorphic expression pattern. Defective testicular development and XY feminization occur when this gene is hemizygous.
Molecular Weight :	67.140kDa inclusive of tags
Tissue specificity :	Testis specific.
Form :	Liquid
Purity :	Proprietary Purification
Storage buffer :	pH: 8.00Constituents:0.3% Glutathione, 0.79% Tris HCl
Storage :	Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.
Sequences of amino acids :	MPNDEAFSKPSTPSEAPHAPGVPPQGRAGGFGKASGALVG AASGSSAGGSSRGGGSGSGASDLGAGSKKSPRLPKCARCR NHGYASPLKGHKRFCMWRDCQCKKCNLIAERQRVMAAQVA LRRQQAQEEELGISHPIPLPSAAELLVKRENNGSNPCLMT ECSGTSQPPPASVPTTAASEGRMVIQDIPAVTSRGHVENT PDLVSDSTYYSSFYQPSLFPYYNNLYNCPQYSMALAADSA SGEVGNPLGGSPVKNSLRGLPGPYVPGQTGNQWQMKNMEN RHAMSSQYRMHSYYPPPSYLGQSVPQFFTFEDAPSYPEAR ASVFSPPSSQDSGLVSLSSSSPISNKSTKAVLECEPASEP SSFTVTPVIEEDE
Sequence Similarities :	Belongs to the DMRT family.Contains 1 DM DNA-binding domain.

Gene Name	DMRT1 doublesex and mab-3 related transcription factor 1 [ Homo sapiens ]
Official Symbol	DMRT1
Synonyms	DMRT1; doublesex and mab-3 related transcription factor 1; doublesex- and mab-3-related transcription factor 1; DM domain expressed in testis 1; DMT1;
Gene ID	1761
mRNA Refseq	NM_021951
Protein Refseq	NP_068770
MIM	602424
Uniprot ID	Q9Y5R6
Chromosome Location	9p24.3
Function	metal ion binding; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity;