Recombinant Human DNAJB8, His-tagged

• Cat.No.: DNAJB8-12069H
• Product Overview: Recombinant Human DNAJB8 protein, fused to His-tag, was expressed in E.coli and purified by Ni-sepharose.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Protein Length: 1-232a.a.
• Description: The protein encoded by this gene belongs to the DNAJ/HSP40 family of proteins that regulate chaperone activity. This family member suppresses aggregation and toxicity of polyglutamine proteins, and the C-terminal tail is essential for this activity. It has been implicated as a cancer-testis antigen and as a cancer stem-like cell antigen involved in renal cell carcinoma.
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 300mM Imidazole and 0.7% Sarcosyl, 15%glycerol.

Gene Information

• Gene Name: DNAJB8 DnaJ (Hsp40) homolog, subfamily B, member 8 [ Homo sapiens ]
• Official Symbol: DNAJB8
• Synonyms: DNAJB8; DnaJ (Hsp40) homolog, subfamily B, member 8; dnaJ homolog subfamily B member 8; MGC33884; DnaJ homolog, subfamily B, member 8; DJ6
• Gene ID: 165721
• mRNA Refseq: NM_153330
• Protein Refseq: NP_699161
• MIM: 611337
• UniProt ID: Q8NHS0
• Chromosome Location: 3q21.3
• Function: heat shock protein binding; unfolded protein binding