Recombinant Human DNMBP, GST-tagged

• Cat.No.: DNMBP-12107H
• Product Overview: Recombinant Human DNMBP protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose.

Specification

• Description: DNMBP belongs to the DBL (MIM 311030) family of guanine nucleotide exchange factors and plays a role in the regulation of cell junctions (Otani et al., 2006 [PubMed 17015620]).
• Source: E.coli
• Species: Human
• Tag: GST
• Protein length: C-term-351a.a.
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol.

Gene Information

• Gene Name: DNMBP dynamin binding protein [ Homo sapiens ]
• Official Symbol: DNMBP
• Synonyms: DNMBP; dynamin binding protein; dynamin-binding protein; ARHGEF36; KIAA1010; scaffold protein TUBA; Tuba; TUBA; RP11-114F7.3
• Gene ID: 23268
• mRNA Refseq: NM_015221
• Protein Refseq: NP_056036
• MIM: 611282
• UniProt ID: Q6XZF7
• Chromosome Location: 10q24.31
• Pathway: Regulation of CDC42 activity, organism-specific biosystem
• Function: Rho guanyl-nucleotide exchange factor activity; guanyl-nucleotide exchange factor activity; protein binding