Recombinant Human DNMBP, His-tagged

• Cat.No.: DNMBP-28369TH
• Product Overview: Recombinant fragment, corresponding to amino acids 1400-1577 of Human DNMBP with N terminal His tag; 178 amino acids, 44kDa.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Protein Length: 1400-1577 a.a.
• Description: DNMBP belongs to the DBL (MIM 311030) family of guanine nucleotide exchange factors and plays a role in the regulation of cell junctions (Otani et al.
• Conjugation: His
• Tissue specificity: Detected in heart, brain, lung, liver, skeletal muscle, kidney and pancreas.
• Form: Lyophilised:Reconstitute with 84 μl aqua dest.
• Storage buffer: Preservative: NoneConstituents: 0.5% Trehalose, 6M Urea, 100mM Sodium phosphate, 10mM Sodium chloride, pH 4.5
• Storage: Shipped at 4°C. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.
• Sequences of amino acids: QKQPQDASPPPKECDQGTLSASLNPSNSESSPSRCPSDPD STSQPRSGDSADVARDVKQPTATPRSYRNFRHPEIVGY SVPGRNGQSQDLVKGCARTAQAPEDRSTEPDGSEAEGN QVYFAVYTFKARNPNELSVSANQKLKILEFKDVTGNTEWW LAEVNGKKGYVPSNYIRKTEYT
• Sequence Similarities: Contains 1 BAR domain.Contains 1 DH (DBL-homology) domain.Contains 6 SH3 domains.

Gene Information

• Gene Name: DNMBP dynamin binding protein [ Homo sapiens ]
• Official Symbol: DNMBP
• Synonyms: DNMBP; dynamin binding protein; dynamin-binding protein; ARHGEF36; KIAA1010; scaffold protein TUBA; Tuba
• Gene ID: 23268
• mRNA Refseq: NM_015221
• Protein Refseq: NP_056036
• MIM: 611282
• Uniprot ID: Q6XZF7
• Chromosome Location: 10q24.31
• Pathway: Regulation of CDC42 activity, organism-specific biosystem
• Function: Rho guanyl-nucleotide exchange factor activity; guanyl-nucleotide exchange factor activity; protein binding