Recombinant Human DOCK10 Protein, GST-tagged

• Cat.No.: DOCK10-2804H
• Product Overview: Human DOCK10 full-length ORF ( ADZ15499.1, 1 a.a. - 542 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: This gene encodes a member of the dedicator of cytokinesis protein family. Members of this family are guanosine nucleotide exchange factors for Rho GTPases and defined by the presence of conserved DOCK-homology regions. The encoded protein belongs to the D (or Zizimin) subfamily of DOCK proteins, which also contain an N-terminal pleckstrin homology domain. Alternatively spliced transcript variants that encode different isoforms have been described. [provided by RefSeq, Mar 2014]
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 59.7 kDa
• AA Sequence: MKNSNFPAEVKDLTKRIRTVLMATA QMKEHEKDPEMLVDLQYSLANSYAS TPELRRTWLESMAKIHARNGDLSEA AMCYIHIAALIAEYLKRKGYWKVEK ICTASLLSEDTHPCDSNSLLTTPSG GSMFSMGWPAFLSITPNIKEEGAMK EDSGMQDTPYNENILVEQLYMCVEF LWKSERYELIADVNKPIIAVFEKQR DFKKLSDLYYDIHRSYLKVAEVVNS EKRLFGRYYRVAFYGQGFFEEEEGK EYIYKEPKLTGLSEISQRLLKLYAD KFGADNVKIIQDSNKVNPKDLDPKY AYIQVTYVTPFFEEKEIEDRKTDFE MHHNINRFVFETPFTLSGKKHGGVA EQCKRRTILTTSHLFPYVKKRIQVI SQSSTELNPIEVAIDEMSKKVSELN QLCTMEEVDMIRLQLKLQGSVSVKV NAGPMAYARAFLEETNAKKYPDNQV KLLKEIFRQFADACGQALDVNERLI KEDQLEYQEELRSHYKDMLSELSTV MNEQITGRDDLSKRGVDQTCTRVIS KATPALPTVSISSSAEV
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: DOCK10 dedicator of cytokinesis 10 [ Homo sapiens ]
• Official Symbol: DOCK10
• Synonyms: DOCK10; dedicator of cytokinesis 10; dedicator of cytokinesis protein 10; KIAA0694; ZIZ3; zizimin3; zizimin-3; protein zizimin 3; dopamine receptor interacting protein 2; DRIP2; Nbla10300; DKFZp781A1532
• Gene ID: 55619
• mRNA Refseq: NM_014689
• Protein Refseq: NP_055504
• MIM: 611518
• UniProt ID: Q96BY6