Recombinant Human DPH3 Protein, GST-tagged

• Cat.No.: DPH3-2834H
• Product Overview: Human DPH3 full-length ORF ( ADZ15684.1, 1 a.a. - 82 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: This gene encodes a CSL zinc finger-containing protein that is required for dipthamide biosynthesis. The encoded protein is necessary for the initial step in the modification of a histidine residue in elongation factor-2 to diphthamide. This modified residue is a target for ADP ribosylation by the bacterial toxins diphtheria toxin and Pseudomonas exotoxin A. Alternative splicing results in multiple transcript variants that encode the same isoform. [provided by RefSeq, Feb 2009]
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 9.1 kDa
• AA Sequence: MAVFHDEVEIEDFQYDEDSETYFYP CPCGDNFSITKEDLENGEDVATCPS CSLIIKVIYDKDQFVCGETVPAPSA NKELVKC
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: DPH3 DPH3, KTI11 homolog (S. cerevisiae) [ Homo sapiens ]
• Official Symbol: DPH3
• Synonyms: DESR1; DPH3A; KTI11; ZCSL2; DELGIP; DELGIP1
• Gene ID: 285381
• mRNA Refseq: NM_206831
• Protein Refseq: NP_996662
• MIM: 608959
• UniProt ID: Q96FX2