| Description : |
This gene encodes a protein that is a member of the M49 family of metallopeptidases. This cytoplasmic protein binds a single zinc ion with its zinc-binding motif (HELLGH) and has post-proline dipeptidyl aminopeptidase activity, cleaving Xaa-Pro dipeptides from the N-termini of proteins. Increased activity of this protein is associated with endometrial and ovarian cancers. Alternatively spliced transcript variants have been found for this gene. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Myc/DDK |
| Molecular Mass : |
82.6 kDa |
| AA Sequence : |
MADTQYILPNDIGVSSLDCREAFRL LSPTERLYAYHLSRAAWYGGLAVLL QTSPEAPYIYALLSRLFRAQDPDQL RQHALAEGLTEEEYQAFLVYAAGVY SNMGNYKSFGDTKFVPNLPKEKLER VILGSEAAQQHPEEVRGLWQTCGEL MFSLEPRLRHLGLGKEGITTYFSGN CTMEDAKLAQDFLDSQNLSAYNTRL FKEVDGEGKPYYEVRLASVLGSEPS LDSEVTSKLKSYEFRGSPFQVTRGD YAPILQKVVEQLEKAKAYAANSHQG QMLAQYIESFTQGSIEAHKRGSRFW IQDKGPIVESYIGFIESYRDPFGSR GEFEGFVAVVNKAMSAKFERLVASA EQLLKELPWPPTFEKDKFLTPDFTS LDVLTFAGSGIPAGINIPNYDDLRQ TEGFKNVSLGNVLAVAYATQREKLT FLEEDDKDLYILWKGPSFDVQVGLH ELLGHGSGKLFVQDEKGAFNFDQET VINPETGEQIQSWYRSGETWDSKFS TIASSYEECRAESVGLYLCLHPQVL EIFGFEGADAEDVIYVNWLNMVRAG LLALEFYTPEAFNWRQAHMQARFVI LRVLLEAGEGLVTITPTTGSDGRPD ARVRLDRSKIRSVGKPALERFLRRL QVLKSTGDVAGGRALYEGYATVTDA PPECFLTLRDTVLLRKESRKLIVQP NTRLEGSDVQLLEYEASAAGLIRSF SERFPEDGPELEEILTQLATADARF WKGPSEAPSGQATRTRPLEQKLISE EDLAANDILDYKDDDDKV |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : |
50 μg/mL as determined by BCA |
| Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
