Recombinant Human DPP9

• Cat.No.: DPP9-28434TH
• Product Overview: Recombinant full length Human DPP9 with N terminal proprietary tag expressed in a Baculovirus infected Sf9 cell expression system, 122.6 kDa.

Specification

• Description: This gene encodes a protein that is a member of the S9B family in clan SC of the serine proteases. The protein has been shown to have post-proline dipeptidyl aminopeptidase activity, cleaving Xaa-Pro dipeptides from the N-termini of proteins. Although the activity of this protein is similar to that of dipeptidyl peptidase 4 (DPP4), it does not appear to be membrane bound. In general, dipeptidyl peptidases appear to be involved in the regulation of the activity of their substrates and have been linked to a variety of diseases including type 2 diabetes, obesity and cancer. Several transcript variants of this gene have been described but not fully characterized.
• Tissue specificity: Ubiquitously expressed, with highest levels in liver, heart and muscle, and lowest levels in brain.
• Biological activity: Specific Activity: 536 U/ug. One U =1 pmol/min.
• Form: Liquid
• Storage buffer: Preservative: NoneConstituents: 50% Glycerol, 0.05% Tween 20, 3mM DTT, 25mM Tris HCl, 100mM Sodium chloride, pH 8.0
• Storage: Aliquot and store at -80°C. Avoid repeated freeze / thaw cycles.
• Sequence Similarities: Belongs to the peptidase S9B family. DPPIV subfamily.

Gene Information

• Gene Name: DPP9 dipeptidyl-peptidase 9 [ Homo sapiens ]
• Official Symbol: DPP9
• Synonyms: DPP9; dipeptidyl-peptidase 9; dipeptidylpeptidase 9; dipeptidyl peptidase 9
• Gene ID: 91039
• mRNA Refseq: NM_139159
• Protein Refseq: NP_631898
• MIM: 608258
• Uniprot ID: Q86TI2
• Chromosome Location: 19p13.3
• Function: aminopeptidase activity; peptidase activity; serine-type peptidase activity