| Description : |
This gene encodes a cytoplasmic protein that catalyzes the conversion of uridine residues to dihydrouridine in the D-loop of tRNA. The resulting modified bases confer enhanced regional flexibility to tRNA. The encoded protein may increase the rate of translation by inhibiting an interferon-induced protein kinase. This gene has been implicated in pulmonary carcinogenesis. Alternatively spliced transcript variants have been described for this gene. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Myc/DDK |
| Molecular Mass : |
55.1 kDa |
| AA Sequence : |
MILNSLSLCYHNKLILAPMVRVGTL PMRLLALDYGADIVYCEELIDLKMI QCKRVVNEVLSTVDFVAPDDRVVFR TCEREQNRVVFQMGTSDAERALAVA RLVENDVAGIDVNMGCPKQYSTKGG MGAALLSDPDKIEKILSTLVKGTRR PVTCKIRILPSLEDTLSLVKRIERT GIAAIAVHGRKREERPQHPVSCEVI KAIADTLSIPVIANGGSHDHIQQYS DIEDFRQATAASSVMVARAAMWNPS IFLKEGLRPLEEVMQKYIRYAVQYD NHYTNTKYCLCQMLREQLESPQGRL LHAAQSSREICEAFGLGAFYEETTQ ELDAQQARLSAKTSEQTGEPAEDTS GVIKMAVKFDRRAYPAQITPKMCLL EWCRREKLAQPVYETVQRPLDRLFS SIVTVAEQKYQSTLWDKSKKLAEQA AAIVCLRSQGLPEGRLGEESPSLHK RKREAPDQDPGGPRAQELAQPGDLC KKPFVALGSGEESPLEGWTRTRPLE QKLISEEDLAANDILDYKDDDDKV |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : |
50 μg/mL as determined by BCA |
| Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
