Recombinant Human ECH1, His-tagged
Cat.No. : | ECH1-28224TH |
Product Overview : | Recombinant full length Human ECH1, amino acids 34-328 with N terminal His tag; 316 amino acids with a predicted MWt 34.4 kDa including tag. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes a member of the hydratase/isomerase superfamily. The gene product shows high sequence similarity to enoyl-coenzyme A (CoA) hydratases of several species, particularly within a conserved domain characteristic of these proteins. The encoded protein, which contains a C-terminal peroxisomal targeting sequence, localizes to the peroxisome. The rat ortholog, which localizes to the matrix of both the peroxisome and mitochondria, can isomerize 3-trans,5-cis-dienoyl-CoA to 2-trans,4-trans-dienoyl-CoA, indicating that it is a delta3,5-delta2,4-dienoyl-CoA isomerase. This enzyme functions in the auxiliary step of the fatty acid beta-oxidation pathway. Expression of the rat gene is induced by peroxisome proliferators. |
Protein length : | 295 amino acids |
Conjugation : | HIS |
Molecular Weight : | 34.400kDa inclusive of tags |
Source : | E. coli |
Form : | Liquid |
Purity : | >90% by SDS-PAGE |
Storage buffer : | Preservative: NoneConstituents: 10% Glycerol, 50mM Sodium chloride, 20mM Tris HCl, 1mM DTT, pH 8.0 |
Storage : | Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. |
Sequences of amino acids : | MGSSHHHHHHSSGLVPRGSHMTGSS AQEAASGVALGEAPDHSYESLRVTS AQKHVLHVQLNRPNKRNAMNKVFWR EMVECFNKISRDADCRAVVISGAGK MFTAGIDLMDMASDILQPKGDDVAR ISWYLRDIITRYQETFNVIERCPKP VIAAVHGGCIGGGVDLVTACDIRYC AQDAFFQVKEVDVGLAADVGTLQRL PKVIGNQSLVNELAFTARKMMADEA LGSGLVSRVFPDKEVMLDAALALAA EISSKSPVAVQSTKVNLLYSRDHSV AESLNYVASWNMSMLQTQDLVKSVQ ATTENKELKTVTFSKL |
Sequence Similarities : | Belongs to the enoyl-CoA hydratase/isomerase family. |
Gene Name : | ECH1 enoyl CoA hydratase 1, peroxisomal [ Homo sapiens ] |
Official Symbol : | ECH1 |
Synonyms : | ECH1; enoyl CoA hydratase 1, peroxisomal; enoyl Coenzyme A hydratase 1, peroxisomal; delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial; HPXEL; |
Gene ID : | 1891 |
mRNA Refseq : | NM_001398 |
Protein Refseq : | NP_001389 |
MIM : | 600696 |
Uniprot ID : | Q13011 |
Chromosome Location : | 19q13.1 |
Pathway : | Fatty Acid Biosynthesis, organism-specific biosystem; Peroxisome, organism-specific biosystem; Peroxisome, conserved biosystem; |
Function : | enoyl-CoA hydratase activity; isomerase activity; protein binding; |
Products Types
◆ Recombinant Protein | ||
ECH1-1658R | Recombinant Rat ECH1 Protein, His (Fc)-Avi-tagged | +Inquiry |
ECH1-2621M | Recombinant Mouse ECH1 Protein, His (Fc)-Avi-tagged | +Inquiry |
ECH1-3030H | Recombinant Human ECH1 Protein, GST-tagged | +Inquiry |
Ech1-2716M | Recombinant Mouse Ech1 Protein, Myc/DDK-tagged | +Inquiry |
ECH1-1577Z | Recombinant Zebrafish ECH1 | +Inquiry |
◆ Lysates | ||
ECH1-6730HCL | Recombinant Human ECH1 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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