| Description : |
This gene encodes a soluble protein that is involved in endochondral bone formation, angiogenesis, and tumor biology. It also interacts with a variety of extracellular and structural proteins, contributing to the maintenance of skin integrity and homeostasis. Mutations in this gene are associated with lipoid proteinosis disorder (also known as hyalinosis cutis et mucosae or Urbach-Wiethe disease) that is characterized by generalized thickening of skin, mucosae and certain viscera. Alternatively spliced transcript variants encoding distinct isoforms have been described for this gene. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Myc/DDK |
| Molecular Mass : |
60.7 kDa |
| AA Sequence : |
MGTTARAALVLTYLAVASAASEGGF TATGQRQLRPEHFQEVGYAAPPSPP LSRSLPMDHPDSSQHGPPFEGQSQV QPPPSQEATPLQQEKLLPAQLPAEK EVGPPLPQEAVPLQKELPSLQHPNE QKEGMPAPFGDQSHPEPESWNAAQH CQQDRSQGGWGHRLDGFPPGRPSPD NLNQICLPNRQHVVYGPWNLPQSSY SHLTRQGETLNFLEIGYSRCCHCRS HTNRLECAKLVWEEAMSRFCEAEFS VKTRPHWCCTRQGEARFSCFQEEAP QPHYQLRACPSHQPDISSGLELPFP PGVPTLDNIKNICHLRRFRSVPRNL PATDPLQRELLALIQLEREFQRCCR QGNNHTCTWKAWEDTLDKYCDREYA VKTHHHLCCRHPPSPTRDECFARRA PYPNYDRDILTIDISRVTPNLMGHL CGNQRVLTKHKHIPGLIHNMTARCC DLPFPEQACCAEEEKLTFINDLCGP RRNIWRDPALCCYLSPGDEQVNCFN INYLRNVALVSGDTENAKGQGEQGS TGGTNISSTSEPKEETRTRPLEQKL ISEEDLAANDILDYKDDDDKV |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : |
50 μg/mL as determined by BCA |
| Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
