|Product Overview :||Recombinant Human EFNA1(Asp19-Ser182) fused with His tag at the C-terminus was produced in HEK293.|
|Description :||Ephrin-A1 is a member of the A-type ephrin family of cell surface proteins that function as ligands for the A-type Eph receptor tyrosine kinase family. Ephrin-A1 can be induced by TNF and IL1B. Its expression levels can be down-regulated in primary glioma tissues compared to the normal tissues. The soluble monomeric form is expressed in the glioblastoma multiforme (GBM) and breast cancer cells. Soluble Ephrin-A1 is necessary for the transformation of HeLa and SK-BR3 cells and participates in the relocalization of EPHA2 away from sites of cell-cell contact during transformation. Ephrin-A1 plays an important role in angiogenesis and tumor neovascularization.|
|Form :||Lyophilized from a 0.2 μm filtered solution of 20mM PB,150mM NaCl,pH7.4.|
|Protein length :||Asp19-Ser182|
|AA sequence :||DRHTVFWNSSNPKFRNEDYTIHVQLNDYVDIICPHYEDHSVADAAMEQYILYLVEHEEYQLCQPQ SKDQVRWQCNRPSAKHGPEKLSEKFQRFTPFTLGKEFKEGHSYYYISKPIHQHEDRCLRLKVTVS GKITHSPQAHVNPQEKRLAADDPEVRVLHSIAHSVDHHHHHH|
|Endotoxin :||Less than 0.1 ng/µg (1 IEU/µg) as determined by LAL test.|
|Purity :||Greater than 95% as determined by reducing SDS-PAGE.|
|Storage :||Lyophilized protein should be stored at < -20 centigrade, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7 centigrade for 2-7 days.
Aliquots of reconstituted samples are stable at < -20 centigrade for 3 months.
|Reconstitution :||Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
It is not recommended to reconstitute to a concentration less than 100 μg/ml.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
|Shipping :||The product is shipped at ambient temperature.|
|Gene Name :||EFNA1 ephrin-A1 [ Homo sapiens ]|
|Official Symbol :||EFNA1|
|Synonyms :||EFNA1; ephrin-A1; EPLG1, TNFAIP4; ECKLG; LERK1; TNF alpha-induced protein 4; ligand of eph-related kinase 1; immediate early response protein B61; eph-related receptor tyrosine kinase ligand 1; tumor necrosis factor alpha-induced protein 4; tumor necrosis factor, alpha-induced protein 4; B61; EFL1; EPLG1; LERK-1; TNFAIP4;|
|Gene ID :||1942|
|mRNA Refseq :||NM_004428|
|Protein Refseq :||NP_004419|
|UniProt ID :||P20827|