Recombinant Human EIF2AK3 Protein, MYC/DDK-tagged
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Cat.No. : | EIF2AK3-337H |
Product Overview : | Recombinant Human EIF2AK3 fused with MYC/DDK tag at C-terminal was expressed in HEK293. |
Description : | The protein encoded by this gene phosphorylates the alpha subunit of eukaryotic translation-initiation factor 2, leading to its inactivation, and thus to a rapid reduction of translational initiation and repression of global protein synthesis. This protein is thought to modulate mitochondrial function. It is a type I membrane protein located in the endoplasmic reticulum (ER), where it is induced by ER stress caused by malfolded proteins. Mutations in this gene are associated with Wolcott-Rallison syndrome. |
Source : | HEK293 |
Species : | Human |
Tag : | MYC/DDK |
Form : | 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
Molecular Mass : | 122.1 kDa |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Concentration : | >50 ug/mL as determined by microplate BCA method |
Gene Name : | EIF2AK3 eukaryotic translation initiation factor 2-alpha kinase 3 [ Homo sapiens ] |
Official Symbol : | EIF2AK3 |
Synonyms : | EIF2AK3; eukaryotic translation initiation factor 2-alpha kinase 3; PEK; PERK; hsPEK; pancreatic EIF2-alpha kinase; PRKR-like endoplasmic reticulum kinase; eukaryotic translation initiation factor 2 alpha kinase 3; WRS; DKFZp781H1925; |
Gene ID : | 9451 |
mRNA Refseq : | NM_004836 |
Protein Refseq : | NP_004827 |
MIM : | 604032 |
UniProt ID : | Q9NZJ5 |
◆ Recombinant Protein
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Eif2ak3-2772M | Recombinant Mouse Eif2ak3 Protein, Myc/DDK-tagged | +Inquiry |
EIF2AK3-1020H | Recombinant Human EIF2AK3 Protein, His-tagged | +Inquiry |
EIF2AK3-2045R | Recombinant Rat EIF2AK3 Protein | +Inquiry |
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◆ Lysates
EIF2AK3-6673HCL | Recombinant Human EIF2AK3 293 Cell Lysate | +Inquiry |
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EIF1EIF1AXEIF1AYEIF2AEIF2AK1EIF2AK2EIF2B1EIF2B2EIF2C1EIF2C2EIF2S1EIF3GEIF3HEIF3IEIF3KEIF4EEIF4E2EIF4EBP1EIF4EBP2EIF5AEIF5A2EIF6EIF2S2EIF4BEIF4G1EIF2AK4EIF4A3EIF4EBP3EIF4ENIF1EIF4G2EIF4G3EIF4HEIF5EIF3JEIF2C4EIF2S3EIF3AEIF5BEIF2AK3EIF2C3EIF-2ALPHAEIF2B3EIF2DEIF3DEIF3EEIF3MEIF4A1EIF3FEIF2C5EIF2B5EIF5AL1EIF3BEIF4A2EIF3LEIF3CEIF1ADEIF1AEif2s3xEif2s3yEif3s6ipEIF2B4EIF3CLEif4e1bEif4e3
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