Recombinant Human EIF4A1 Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: EIF4A1-6247H
• Product Overview: EIF4A1 MS Standard C13 and N15-labeled recombinant protein (NP_001407) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Species: Human
• Source: HEK293
• Tag: DDK&Myc
• Description: EIF4A1 (Eukaryotic Translation Initiation Factor 4A1) is a Protein Coding gene. Diseases associated with EIF4A1 include Noonan Syndrome 6. Among its related pathways are Translation Translation regulation by Alpha-1 adrenergic receptors and Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S. Gene Ontology (GO) annotations related to this gene include nucleic acid binding and hydrolase activity. An important paralog of this gene is EIF4A2.
• Molecular Mass: 46.2 kDa
• AA Sequence: MSASQDSRSRDNGPDGMEPEGVIESNWNEIVDSFDDMNLSESLLRGIYAYGFEKPSAIQQRAILPCIKGYDVIAQAQSGTGKTATFAISILQQIELDLKATQALVLAPTRELAQQIQKVVMALGDYMGASCHACIGGTNVRAEVQKLQMEAPHIIVGTPGRVFDMLNRRYLSPKYIKMFVLDEADEMLSRGFKDQIYDIFQKLNSNTQVVLLSATMPSDVLEVTKKFMRDPIRILVKKEELTLEGIRQFYINVEREEWKLDTLCDLYETLTITQAVIFINTRRKVDWLTEKMHARDFTVSAMHGDMDQKERDVIMREFRSGSSRVLITTDLLARGIDVQQVSLVINYDLPTNRENYIHRIGRGGRFGRKGVAINMVTEEDKRTLRDIETFYNTSIEEMPLNVADLISGPTRTRPLEQKLISEEDLAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: EIF4A1 eukaryotic translation initiation factor 4A1 [ Homo sapiens (human) ]
• Official Symbol: EIF4A1
• Synonyms: EIF4A1; eukaryotic translation initiation factor 4A1; EIF4A, eukaryotic translation initiation factor 4A, isoform 1; eukaryotic initiation factor 4A-I; DDX2A; EIF 4A; eukaryotic initiation factor 4AI; ATP-dependent RNA helicase eIF4A-1; eukaryotic translation initiation factor 4A, isoform 1; EIF4A; EIF-4A; eIF4A-I; eIF-4A-I
• Gene ID: 1973
• mRNA Refseq: NM_001416
• Protein Refseq: NP_001407
• MIM: 602641
• UniProt ID: P60842