Recombinant Human ELANE Protein, GST-tagged
Welcome! For price inquiries, please feel free to contact us through the form below. We will get back to you as soon as possible.
Cat.No. : | ELANE-3222H Optional Service: Optional requirements on this protein |
Product Overview : | Human ELA2 partial ORF ( NP_001963, 168 a.a. - 267 a.a.) recombinant protein with GST-tag at N-terminal. |
Description : | Elastases form a subfamily of serine proteases that hydrolyze many proteins in addition to elastin. Humans have six elastase genes which encode structurally similar proteins. The encoded preproprotein is proteolytically processed to generate the active protease. Following activation, this protease hydrolyzes proteins within specialized neutrophil lysosomes, called azurophil granules, as well as proteins of the extracellular matrix. The enzyme may play a role in degenerative and inflammatory diseases through proteolysis of collagen-IV and elastin. This protein also degrades the outer membrane protein A (OmpA) of E. coli as well as the virulence factors of such bacteria as Shigella, Salmonella and Yersinia. Mutations in this gene are associated with cyclic neutropenia and severe congenital neutropenia (SCN). This gene is present in a gene cluster on chromosome 19. [provided by RefSeq, Jan 2016] |
Source : | Wheat Germ |
Species : | Human |
Tag : | GST |
Molecular Mass : | 36.74 kDa |
AA Sequence : | VLQELNVTVV TSLCRRSNVC TLVRGRQAGV CFGDSGSPLV CNGLIHGIAS FVRGGCASGL YPDAFAPVAQ FVNWIDSIIQ RSEDNPCPHP RDPDPASRTH |
Applications : | Enzyme-linked Immunoabsorbent Assay Western Blot (Recombinant protein) Antibody Production Protein Array |
Notes : | Best use within three months from the date of receipt of this protein. |
Storage : | Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing. |
Storage Buffer : | 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer. |
Quality Control Testing : |
![]() 12.5% SDS-PAGE Stained with Coomassie Blue. |
Gene Name : | ELANE elastase, neutrophil expressed [ Homo sapiens (human) ] |
Official Symbol : | ELANE |
Synonyms : | ELANE; elastase, neutrophil expressed; Elastase, Neutrophil Expressed; Medullasin 2; Bone Marrow Serine Protease; Elastase 2, Neutrophil; Neutrophil Elastase; Leukocyte Elastase; PMN Elastase; Elastase-2; ELA2; HLE; Granulocyte-Derived Elastase; Polymorphonuclear Elastase; Human Leukocyte Elastase; EC 3.4.21.37; EC 3.4.21; PMN-E; SCN1; HNE; GE; NE; neutrophil elastase; PMN elastase; bone marrow serine protease; elastase 2, neutrophil; elastase-2; granulocyte-derived elastase; leukocyte elastase; medullasin; polymorphonuclear elastase |
Gene ID : | 1991 |
mRNA Refseq : | NM_001972 |
Protein Refseq : | NP_001963 |
MIM : | 130130 |
UniProt ID : | P08246 |
◆ Recombinant Protein
ELANE-1197H | Recombinant Human ELANE Protein, GST-tagged | +Inquiry |
Elane-903M | Recombinant Mouse Elane Protein, His-tagged | +Inquiry |
Elane-1419M | Recombinant Mouse Elane Protein, His-tagged | +Inquiry |
ELANE-2171H | Recombinant Human ELANE Protein, His-tagged | +Inquiry |
ELANE-902D | Recombinant Dog ELANE Protein, His-tagged | +Inquiry |
|
◆ Native Protein
ELANE-3221H | Native Human ELANE Protein | +Inquiry |
ELANE-8104H | Native Human Neutrophil Elastase | +Inquiry |
ELANE-001H | Native Human ELANE Protein | +Inquiry |
|
◆ Lysates
ELANE-2381MCL | Recombinant Mouse ELANE cell lysate | +Inquiry |
|
◆ Assay kits
Kit-0323 | Neutrophil elastase colorimetric drug discovery Kit | +Inquiry |
Kit-0322 | Neutrophil Elastase Activity Assay Kit | +Inquiry |
|
Easy access to products and services you need from our library via powerful searching tools.
Copyright © 2022 Creative BioMart. All Rights Reserved. Terms and Conditions | Privacy Policy