Recombinant Human EOGT Protein, GST-Tagged EOGT-0045H

Recombinant Human EOGT Protein, GST-Tagged

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Recombinant Human EOGT Protein, GST-Tagged

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Cat.No. : EOGT-0045H
Product Overview : Human EOGT full-length ORF (NP_775925.1, 1 a.a. - 443 a.a.) recombinant protein with GST-tag at N-terminal.
Description : This gene encodes an enzyme that acts in the lumen of the endoplasmic reticulum to catalyze the transfer of N-acetylglucosamine to serine or threonine residues of extracellular-targeted proteins. This enzyme modifies proteins containing eukaryotic growth factor (EGF)-like domains, including the Notch receptor, thereby regulating developmental signalling. Mutations in this gene have been observed in individuals with Adams-Oliver syndrome 4. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2015]
Source : Wheat Germ
Species : Human
Tag : GST
Molecular Mass : 78.7 kDa
AA Sequence : MLMLFVFGVLLHEVS LSGQNEAPPNTHSIP GEPLYNYASIRLPEE HIPFFLHNNRHIATV CRKDSLCPYKKHLEK LKYCWGYEKSCKPEF RFGYPVCSYVDMGWT DTLESAEDIFWKQAD FGYARERLEEMHVLC QPKETSDSSLVCSRY LQYCRATNLYLDLRN IKRNHDRFKEDFFQS GEIGGHCKLDIRTLT SEGQRKSPLQSWFAE LQSYTQLNFRPIEDA KCDIVIEKPTYFMKL DAGVNMYHHFCDFIN LYITQHVNNSFSTDV YIVMWDTDGKIRVTI LARSTEYRKILNQNE LVNALKTVSTFEVQI VDYKYRELGFLDQLR ITHNTDIFIGMHGAG LTHLLFLPDWAAVFE LYNCEDERCYLDLAR LRGVHYITWRRQNKV FPQDKGHHPTLGEHP KFTNYSFDVEEFMYL VLQAADHVLQHPKWP FKKKHDEL
Applications : Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
Notes : Best use within three months from the date of receipt of this protein.
Storage : Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
Storage Buffer : 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Quality Control Testing :

12.5% SDS-PAGE Stained with Coomassie Blue.

Gene Name : EOGT EGF domain specific O-linked N-acetylglucosamine transferase [ Homo sapiens (human) ]
Official Symbol : EOGT
Synonyms : EOGT; EGF domain specific O-linked N-acetylglucosamine transferase; C3ORF64; chromosome 3 open reading frame 64; uncharacterized glycosyltransferase AER61; AER61; AER61 glycosyltransferase; FLJ33770; FLJ13078; FLJ41219; MGC34132; EGF Domain Specific O-Linked N-Acetylglucosamine Transferase; EGF Domain-Specific O-Linked N-Acetylglucosamine (GlcNAc) Transferase; Extracellular O-Linked N-Acetylglucosamine Transferase; EGF Domain-Specific O-Linked N-Acetylglucosamine Transferase; Chromosome 3 Open Reading Frame 64; EGF-O-GlcNAc Transferase; EC 2.4.1.255 4
Gene ID : 285203
mRNA Refseq : NM_173654
Protein Refseq : NP_775925
MIM : 614789
UniProt ID : Q5NDL2

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