Recombinant Human EOGT Protein, GST-Tagged

• Cat.No.: EOGT-0045H
• Product Overview: Human EOGT full-length ORF (NP_775925.1, 1 a.a. - 443 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: This gene encodes an enzyme that acts in the lumen of the endoplasmic reticulum to catalyze the transfer of N-acetylglucosamine to serine or threonine residues of extracellular-targeted proteins. This enzyme modifies proteins containing eukaryotic growth factor (EGF)-like domains, including the Notch receptor, thereby regulating developmental signalling. Mutations in this gene have been observed in individuals with Adams-Oliver syndrome 4. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2015]
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 78.7 kDa
• AA Sequence: MLMLFVFGVLLHEVSLSGQNEAPPN THSIPGEPLYNYASIRLPEEHIPFF LHNNRHIATVCRKDSLCPYKKHLEK LKYCWGYEKSCKPEFRFGYPVCSYV DMGWTDTLESAEDIFWKQADFGYAR ERLEEMHVLCQPKETSDSSLVCSRY LQYCRATNLYLDLRNIKRNHDRFKE DFFQSGEIGGHCKLDIRTLTSEGQR KSPLQSWFAELQSYTQLNFRPIEDA KCDIVIEKPTYFMKLDAGVNMYHHF CDFINLYITQHVNNSFSTDVYIVMW DTDGKIRVTILARSTEYRKILNQNE LVNALKTVSTFEVQIVDYKYRELGF LDQLRITHNTDIFIGMHGAGLTHLL FLPDWAAVFELYNCEDERCYLDLAR LRGVHYITWRRQNKVFPQDKGHHPT LGEHPKFTNYSFDVEEFMYLVLQAA DHVLQHPKWPFKKKHDEL
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: EOGT EGF domain specific O-linked N-acetylglucosamine transferase [ Homo sapiens (human) ]
• Official Symbol: EOGT
• Synonyms: EOGT; EGF domain specific O-linked N-acetylglucosamine transferase; C3ORF64; chromosome 3 open reading frame 64; uncharacterized glycosyltransferase AER61; AER61; AER61 glycosyltransferase; FLJ33770; FLJ13078; FLJ41219; MGC34132; EGF Domain Specific O-Linked N-Acetylglucosamine Transferase; EGF Domain-Specific O-Linked N-Acetylglucosamine (GlcNAc) Transferase; Extracellular O-Linked N-Acetylglucosamine Transferase; EGF Domain-Specific O-Linked N-Acetylglucosamine Transferase; Chromosome 3 Open Reading Frame 64; EGF-O-GlcNAc Transferase; EC 2.4.1.255 4
• Gene ID: 285203
• mRNA Refseq: NM_173654
• Protein Refseq: NP_775925
• MIM: 614789
• UniProt ID: Q5NDL2