"EP300" Related Products


Recombinant Human EP300 protein, GST-tagged

Cat.No.: EP300-43H
Product Overview: Recombinant Human EP300 Bromodomain (aa 1091 to 1190) fused with GST tag at N-terminal was expressed in E. coli.
Description: P300 is an important regulator of cell function and serves to integrate a number of key cell signaling pathways. P300 contains intrinsic histone acetylatransferase (HAT) activity and serves as a co-activator for a large number of transcription factors. The bromodomain of P300 specifically recognizes a number of acetylated proteins, including histones and transcription factors. The P300 gene is mutated in Rubinestein-Taybi Syndrome, a rare developmental disorder.
Source: E. coli
Species: Human
Tag : GST
Form: Recombinant GST-tagged protein at 1 mg/ml in 20 mM Tris-HCl pH 8.0, 200 mM NaCl, 1 mM DTT, 20% glycerol.
Molecular Mass: 46 kDa
Applications: Recombinant P300 Bromodomain is useful for protein binding and screening experiments examining acetylated protein substrates.
Storage: Stable for six months at -80 centigrade from date of receipt. For best results, aliquot and avoid multiple freeze/thaws.
Concentration: 1 mg/ml
Gene Name: EP300 E1A binding protein p300 [ Homo sapiens ]
Official Symbol: EP300
Synonyms: EP300; E1A binding protein p300; histone acetyltransferase p300; KAT3B; p300; p300 HAT; E1A-binding protein, 300kD; E1A-associated protein p300; RSTS2;
Gene ID: 2033
mRNA Refseq: NM_001429
Protein Refseq: NP_001420
MIM: 602700
UniProt ID: Q09472
Chromosome Location: 22q13.2
Pathway: ATF-2 transcription factor network, organism-specific biosystem; Adherens junction, organism-specific biosystem; Adherens junction, conserved biosystem; Androgen Receptor Signaling Pathway, organism-specific biosystem; BMAL1:CLOCK/NPAS2 Activates Circadian Expression, organism-specific biosystem; C-MYB transcription factor network, organism-specific biosystem; Cell cycle, organism-specific biosystem;

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Optional requirements on this protein    +Expand
C-fusion    N-fusion   Non-tagged
His    GST   Fc   Others
<1.0 eu/μg    <0.1 eu/μg   <0.01 eu/μg   Not required
Monomer Isolation    Dimer Isolation    Not required
>80% by SDS-PAGE    >90% by SDS-PAGE   >95% by SDS-PAGE   Others

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