| Description : |
This gene belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Increased expression of this gene is associated with multiple forms of carcinoma. Alternative splicing results in multiple transcript variants. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Myc/DDK |
| Molecular Mass : |
111.9 kDa |
| AA Sequence : |
MVFQTRYPSWIILCYIWLLRFAHTG EAQAAKEVLLLDSKAQQTELEWISS PPNGWEEISGLDENYTPIRTYQVCQ VMEPNQNNWLRTNWISKGNAQRIFV ELKFTLRDCNSLPGVLGTCKETFNL YYYETDYDTGRNIRENLYVKIDTIA ADESFTQGDLGERKMKLNTEVREIG PLSKKGFYLAFQDVGACIALVSVKV YYKKCWSIIENLAIFPDTVTGSEFS SLVEVRGTCVSSAEEEAENAPRMHC SAEGEWLVPIGKCICKAGYQQKGDT CEPCGRGFYKSSSQDLQCSRCPTHS FSDKEGSSRCECEDGYYRAPSDPPY VACTRPPSAPQNLIFNINQTTVSLE WSPPADNGGRNDVTYRILCKRCSWE QGECVPCGSNIGYMPQQTGLEDNYV TVMDLLAHANYTFEVEAVNGVSDLS RSQRLFAAVSITTGQAAPSQVSGVM KERVLQRSVELSWQEPEHPNGVITE YEIKYYEKDQRERTYSTVKTKSTSA SINNLKPGTVYVFQIRAFTAAGYGN YSPRLDVATLEEATGKMFEATAVSS EQNPVIIIAVVAVAGTIILVFMVFG FIIGRRHCGYSKADQEGDEELYFHF KFPGTKTYIDPETYEDPNRAVHQFA KELDASCIKIERVIGAGEFGEVCSG RLKLPGKRDVAVAIKTLKVGYTEKQ RRDFLCEASIMGQFDHPNVVHLEGV VTRGKPVMIVIEFMENGALDAFLRK HDGQFTVIQLVGMLRGIAAGMRYLA DMGYVHRDLAARNILVNSNLVCKVS DFGLSRVIEDDPEAVYTTTGGKIPV RWTAPEAIQYRKFTSASDVWSYGIV MWEVMSYGERPYWDMSNQDVIKAIE EGYRLPAPMDCPAGLHQLMLDCWQK ERAERPKFEQIVGILDKMIRNPNSL KTPLGTCSRPISPLLDQNTPDFTTF CSVGEWLQAIKMERYKDNFTAAGYN SLESVARMTIEDVMSLGITLVGHQK KIMSSIQTMRAQMLHLHGTGIQVTR TRPLEQKLISEEDLAANDILDYKDD DDKV |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : |
50 μg/mL as determined by BCA |
| Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
