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Active Recombinant Human EPOR Protein, Fc-tagged

Cat.No. : EPOR-29H
Product Overview : Recombinant Human EPOR Protein (Ala 25 - Cys 241) (AAI12154), fused with a human IgG1 Fc tag at the C-terminus, was expressed in HEK293.
  • Specification
  • Gene Information
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Source : HEK293
Species : Human
Tag : Fc
Form : Lyophilized from sterile 50 mM tris, 100 mM glycine, pH7.5, 10% trehalose.
Bio-activity : Measured by its binding ability in a functional ELISA. Immobilized Human EPO, Tag Free at 10μg/mL (100 μL/well) can bind Human EPO R, Fc Tag with a linear range of 0.013-0.12 μg/mL.
Molecular Mass : Recombinant Human EPOR Protein has a calculated MW of 50.1 kDa. The protein migrates as 55-60 kDa on a SDS-PAGE gel under reducing (R) condition due to glycosylation.
Protein length : Ala 25 - Cys 241
Endotoxin : Less than 1.0 EU per μg by the LAL method.
Purity : >92% as determined by SDS-PAGE.
Stability : Samples are stable for up to twelve months from date of receipt at -70ºC.
Storage : Store it under sterile conditions at -20ºC~-70ºC. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution : It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4℃ before opening to recover the entire contents.
Gene Name : EPOR erythropoietin receptor [ Homo sapiens ]
Official Symbol : EPOR
Synonyms : EPOR; erythropoietin receptor; EPO-R; MGC138358;
Gene ID : 2057
mRNA Refseq : NM_000121
Protein Refseq : NP_000112
MIM : 133171
UniProt ID : P19235
Chromosome Location : 19p13.3-p13.2
Pathway : Cytokine-cytokine receptor interaction, organism-specific biosystem; Cytokine-cytokine receptor interaction, conserved biosystem; EPO Receptor Signaling, organism-specific biosystem; EPO signaling pathway, organism-specific biosystem; Hematopoietic cell lineage, organism-specific biosystem; Hematopoietic cell lineage, conserved biosystem; Jak-STAT signaling pathway, organism-specific biosystem;
Function : erythropoietin receptor activity; identical protein binding; protein binding; receptor activity;

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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