Recombinant Human EPRS, GST-tagged

• Cat.No.: EPRS-12504H
• Product Overview: Recombinant Human EPRS protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose.

Specification

• Species: Human
• Source: E.coli
• Tag: GST
• Protein Length: C-term-350a.a.
• Description: Aminoacyl-tRNA synthetases are a class of enzymes that charge tRNAs with their cognate amino acids. The protein encoded by this gene is a multifunctional aminoacyl-tRNA synthetase that catalyzes the aminoacylation of glutamic acid and proline tRNA species. Alternative splicing has been observed for this gene, but the full-length nature and biological validity of the variant have not been determined.
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol.

Gene Information

• Gene Name: EPRS glutamyl-prolyl-tRNA synthetase [ Homo sapiens ]
• Official Symbol: EPRS
• Synonyms: EPRS; glutamyl-prolyl-tRNA synthetase; QARS, QPRS; bifunctional glutamate/proline--tRNA ligase; EARS; GLUPRORS; glutamate tRNA ligase; PARS; proline tRNA ligase; proline-tRNA ligase; prolyl-tRNA synthetase; glutaminyl-tRNA synthetase; proliferation-inducing protein 32; bifunctional aminoacyl-tRNA synthetase; proliferation-inducing gene 32 protein; cell proliferation-inducing gene 32 protein; QARS; QPRS; PIG32; DKFZp313B047
• Gene ID: 2058
• mRNA Refseq: NM_004446
• Protein Refseq: NP_004437
• MIM: 138295
• UniProt ID: P07814
• Chromosome Location: 1q41
• Pathway: Aminoacyl-tRNA biosynthesis, organism-specific biosystem; Aminoacyl-tRNA biosynthesis, conserved biosystem; Aminoacyl-tRNA biosynthesis, eukaryotes, organism-specific biosystem; Aminoacyl-tRNA biosynthesis, eukaryotes, conserved biosystem; Cytosolic tRNA aminoacylation, organism-specific biosystem; Gene Expression, organism-specific biosystem; Metabolic pathways, organism-specific biosystem
• Function: ATP binding; RNA binding; glutamate-tRNA ligase activity; ligase activity; nucleotide binding; proline-tRNA ligase activity; protein binding