| Description : |
This gene encodes a protein that is part of the EGFR pathway. The protein is present at clatherin-coated pits and is involved in receptor-mediated endocytosis of EGF. Notably, this gene is rearranged with the HRX/ALL/MLL gene in acute myelogeneous leukemias. Alternative splicing results in multiple transcript variants encoding distinct isoforms. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Myc/DDK |
| Molecular Mass : |
98.5 kDa |
| AA Sequence : |
MAAAAQLSLTQLSSGNPVYEKYYRQ VDTGNTGRVLASDAAAFLKKSGLPD LILGKIWDLADTDGKGILNKQEFFV ALRLVACAQNGLEVSLSSLNLAVPP PRFHDTSSPLLISGTSAAELPWAVK PEDKAKYDAIFDSLSPVNGFLSGDK VKPVLLNSKLPVDILGRVWELSDID HDGMLDRDEFAVAMFLVYCALEKEP VPMSLPPALVPPSKRKTWVVSPAEK AKYDEIFLKTDKDMDGFVSGLEVRE IFLKTGLPSTLLAHIWSLCDTKDCG KLSKDQFALAFHLISQKLIKGIDPP HVLTPEMIPPSDRASLQKNIIGSSP VADFSAIKELDTLNNEIVDLQREKN NVEQDLKEKEDTIKQRTSEVQDLQD EVQRENTNLQKLQAQKQQVQELLDE LDEQKAQLEEQLKEVRKKCAEEAQL ISSLKAELTSQESQISTYEEELAKA REELSRLQQETAELEESVESGKAQL EPLQQHLQDSQQEISSMQMKLMEMK DLENHNSQLNWCSSPHSILVNGATD YCSLSTSSSETANLNEHVEGQSNLE SEPIHQESPARSSPELLPSGVTDEN EVTTAVTEKVCSELDNNRHSKEEDP FNVDSSSLTGPVADTNLDFFQSDPF VGSDPFKDDPFGKIDPFGGDPFKGS DPFASDCFFRQSTDPFATSSTDPFS AANNSSITSVETLKHNDPFAPGGTV VAASDSATDPFASVFGNESFGGGFA DFSTLSKVNNEDPFRSATSSSVSNV VITKNVFEETSVKSEDEPPALPPKI GTPTRPCPLPPGKRSINKLDSPDPF KLNDPFQPFPGNDSPKEKDPEIFCD PFTSATTTTNKEADPSNFANFSAYP SEEDMIEWAKRESEREEEQRLARLN QQEQEDLELAIALSKSEISEATRTR PLEQKLISEEDLAANDILDYKDDDD KV |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : |
50 μg/mL as determined by BCA |
| Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
