Recombinant Human EPS8 Protein, GST-tagged

• Cat.No.: EPS8-3426H
• Product Overview: Human EPS8 full-length ORF ( NP_004438.3, 1 a.a. - 822 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: This gene encodes a member of the EPS8 family. This protein contains one PH domain and one SH3 domain. It functions as part of the EGFR pathway, though its exact role has not been determined. Highly similar proteins in other organisms are involved in the transduction of signals from Ras to Rac and growth factor-mediated actin remodeling. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized. [provided by RefSeq, Jul 2008]
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 118.3 kDa
• AA Sequence: MNGHISNHPSSFGMYPSQMNGYGSS PTFSQTDREHGSKTSAKALYEQRKN YARDSVSSVSDISQYRVEHLTTFVL DRKDAMITVDDGIRKLKLLDAKGKV WTQDMILQVDDRAVSLIDLESKNEL ENFPLNTIQHCQAVMHSCSYDSVLA LVCKEPTQNKPDLHLFQCDEVKANL ISEDIESAISDSKGGKQKRRPDALR MISNADPSIPPPPRAPAPAPPGTVT QVDVRSRVAAWSAWAADQGDFEKPR QYHEQEETPEMMAARIDRDVQILNH ILDDIEFFITKLQKAAEAFSELSKR KKNKKGKRKGPGEGVLTLRAKPPPP DEFLDCFQKFKHGFNLLAKLKSHIQ NPSAADLVHFLFTPLNMVVQATGGP ELASSVLSPLLNKDTIDFLNYTVNG DERQLWMSLGGTWMKARAEWPKEQF IPPYVPRFRNGWEPPMLNFMGATME QDLYQLAESVANVAEHQRKQEIKRL STEHSSVSEYHPADGYAFSSNIYTR GSHLDQGEAAVAFKPTSNRHIDRNY EPLKTQPKKYAKSKYDFVARNNSEL SVLKDDILEILDDRKQWWKVRNASG DSGFVPNNILDIVRPPESGLGRADP PYTHTIQKQRMEYGPRPADTPPAPS PPPTPAPVPVPLPPSTPAPVPVSKV PANITRQNSSSSDSGGSIVRDSQRH KQLPVDRRKSQMEEVQDELIHRLTI GRSAAQKKFHVPRQNVPVINITYDS TPEDVKTWLQSKGFNPVTVNSLGVL NGAQLFSLNKDELRTVCPEGARVYS QITVQKAALEDSSGSSELQEIMRRR QEKISAAASDSGVESFDEGSSH
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: EPS8 epidermal growth factor receptor pathway substrate 8 [ Homo sapiens ]
• Official Symbol: EPS8
• Synonyms: EPS8; epidermal growth factor receptor pathway substrate 8; epidermal growth factor receptor kinase substrate 8
• Gene ID: 2059
• mRNA Refseq: NM_004447
• Protein Refseq: NP_004438
• MIM: 600206
• UniProt ID: Q12929