Recombinant Human ERAP2 Protein, GST-tagged

• Cat.No.: ERAP2-3439H
• Product Overview: Human ERAP2 full-length ORF ( AAH17927.1, 1 a.a. - 350 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: This gene encodes a zinc metalloaminopeptidase of the M1 protease family that resides in the endoplasmic reticulum and functions in N-terminal trimming antigenic epitopes for presentation by major histocompatibility complex (MHC) class I molecules. Certain mutations in this gene are associated with the inflammatory arthritis syndrome ankylosing spondylitis and pre-eclampsia. This gene is located adjacent to a closely related aminopeptidase gene on chromosome 5. [provided by RefSeq, Jul 2016]
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 66.5 kDa
• AA Sequence: MFHSSAMVNSHRKPMFNIHRGFYCL TAILPQICICSQFSVPSSYHFTEDP GAFPVATNGERFPWQELRLPSVVIP LHYDLFVHPNLTSLDFVASEKIEVL VSNATQFIILHSKDLEITNATLQSE EDSKYMKPGKELKVLSYPAHEQIAL LVPEKLTPHLKYYVAMDFQAKLGDG FEGFYKSTYRTLGGETRILAVTDFE PTQARMAFPCFDEPLFKANFSIKIR RESRHIALSNMPKVKTIELEGGLLE DHFETTVKMSTYLVAYIVCDFHSLS GFTSSGVKVSIYASPDKRNQTHYAL QASLKLLDFYEKYFDIYYPLSKLGM FKFHIIVFIFAHKTCFDLFPLSLSM
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: ERAP2 endoplasmic reticulum aminopeptidase 2 [ Homo sapiens ]
• Official Symbol: ERAP2
• Synonyms: ERAP2; endoplasmic reticulum aminopeptidase 2; L RAP; leukocyte derived arginine aminopeptidase; LRAP; leukocyte-derived arginine aminopeptidase; L-RAP; FLJ23633; FLJ23701; FLJ23807
• Gene ID: 64167
• mRNA Refseq: NM_001130140
• Protein Refseq: NP_001123612
• MIM: 609497
• UniProt ID: Q6P179