| Description : |
This gene encodes a multifunctional actin-bundling protein. It plays a major role in regulating the organization, dimensions, dynamics, and signaling capacities of the actin filament-rich, microvillus-type specializations that mediate sensory transduction in various mechanosensory and chemosensory cells. Mutations in this gene are associated with autosomal recessive neurosensory deafness, and autosomal dominant sensorineural deafness without vestibular involvement. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Myc/DDK |
| Molecular Mass : |
91.6 kDa |
| AA Sequence : |
MALEQALQAARQGELDVLRSLHAAG LLGPSLRDPLDALPVHHAARAGKLH CLRFLVEEAALPAAARARNGATPAH DASATGHLACLQWLLSQGGCRVQDK DNSGATVLHLAARFGHPEVVNWLLH HGGGDPTAATDMGALPIHYAAAKGD FPSLRLLVEHYPEGVNAQTKNGATP LYLACQEGHLEVTQYLVQECGADPH ARAHDGMTPLHAAAQMGHSPVIVWL VSCTDVSLSEQDKDGATAMHFAASR GHTKVLSWLLLHGGEISADLWGGTP LHDAAENGELECCQILVVNGAELDV RDRDGYTAADLSDFNGHSHCTRYLR TVENLSVEHRVLSRDPSAELEAKQP DSGMSSPNTTVSVQPLNFDLSSPTS TLSNYDSCSSSHSSIKGQHPPCGLS SARAADIQSYMDMLNPELGLPRGTI GKPTPPPPPPSFPPPPPPPGTQLPP PPPGYPAPKPPVGPQAADIYMQTKN KLRHVETEALKKELSSCDGHDGLRR QDSSRKPRAFSKQPSTGDYYRQLGR CPGETLAARPGMAHSEEVRARQPAR AGCPRLGPAARGSLEGPSAPPQAAL LPGNHVPNGCAADPKASRELPPPPP PPPPPLPEAASSPPPAPPLPLESAG PGCGQRRSSSSTGSTKSFNMMSPTG DNSELLAEIKAGKSLKPTPQSKGLT TVFSGIGQPAFQPDSPLPSVSPALS PVRSPTPPAAGFQPLLNGSLVPVPP TTPAPGVQLDVEALIPTHDEQGRPI PEWKRQVMVRKMQLKMQEEEEQRRK EEEEEARLASMPAWRRDLLRKKLEE EREQKRKEEERQKQEELRREKEQSE KLRTLGYDESKLAPWQRQVILKKGD IAKYTRTRPLEQKLISEEDLAANDI LDYKDDDDKV |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : |
50 μg/mL as determined by BCA |
| Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
