Recombinant Human ESRRA Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: ESRRA-4797H
• Product Overview: ESRRA MS Standard C13 and N15-labeled recombinant protein (NP_004442) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: The protein encoded by this gene is a nuclear receptor that is most closely related to the estrogen receptor. This protein acts as a site-specific transcription factor and interacts with members of the PGC-1 family of transcription cofactors to regulate the expression of most genes involved in cellular energy production as well as in the process of mitochondrial biogenesis. A processed pseudogene of ESRRA is located on chromosome 13q12.1.
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 45.5 kDa
• AA Sequence: MSSQVVGIEPLYIKAEPASPDSPKG SSETETEPPVALAPGPAPTRCLPGH KEEEDGEGAGPGEQGGGKLVLSSLP KRLCLVCGDVASGYHYGVASCEACK AFFKRTIQGSIEYSCPASNECEITK RRRKACQACRFTKCLRVGMLKEGVR LDRVRGGRQKYKRRPEVDPLPFPGP FPAGPLAVAGGPRKTAAPVNALVSH LLVVEPEKLYAMPDPAGPDGHLPAV ATLCDLFDREIVVTISWAKSIPGFS SLSLSDQMSVLQSVWMEVLVLGVAQ RSLPLQDELAFAEDLVLDEEGARAA GLGELGAALLQLVRRLQALRLEREE YVLLKALALANSDSVHIEDAEAVEQ LREALHEALLEYEAGRAGPGGGAER RRAGRLLLTLPLLRQTAGKVLAHFY GVKLEGKVPMHKLFLEMLEAMMDTR TRPLEQKLISEEDLAANDILDYKDD DDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: ESRRA estrogen-related receptor alpha [ Homo sapiens (human) ]
• Official Symbol: ESRRA
• Synonyms: ESRRA; estrogen-related receptor alpha; ESRL1; steroid hormone receptor ERR1; ERR1; ERRa; ERRalpha; NR3B1; ERR-alpha; estrogen receptor-like 1; estrogen-related nuclear receptor alpha; nuclear receptor subfamily 3 group B member 1
• Gene ID: 2101
• mRNA Refseq: NM_004451
• Protein Refseq: NP_004442
• MIM: 601998
• UniProt ID: P11474