Recombinant Human Estrogen Receptor Binding Site Associated, Antigen, 9, His-tagged

• Cat.No.: EBAG9-385H
• Product Overview: Recombinant human EBAG9 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques,23.4 kDa (207 aa).

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Description: Estrogen receptor binding site associated antigen 9, also known as EBAG9, is a type III transmembrane protein that is predominantly located in the Golgi. This protein is a tumor-associated antigen that is expressed at high frequency in a variety of cancers, such as advanced breast and prostate cancers. As the EBAG9 acts to inhibit the growth of receptor-binding cells and induced apoptosis of immune cells, cancer cells might evade immune surveillance. So immunodetection of EBAG9 expression can be a negative prognostic indicator.
• Sequences of amino acids: MGSSHHHHHH SSGLVPRGSH MRSGRGRKLS GDQITLPTTV DYSSVPKQTD VEEWTSWDED APTSVKIEGG NGNVATQQNS LEQLEPDYFK DMTPTIRKTQ KIVIKKREPL NFGIPDGSTG FSSRLAATQD LPFIHQSSEL GDLDTWQENT NAWEEEEDAA WQAEEVLRQQ KLADREKRAA EQQRKKMEKE AQRLMKKEQN KIGVKLS
• Formulation: Liquid in 20 mM Tris pH 8.0,1 mM DTT, 2 mM EDTA, 10% glycerol
• Purity: > 90% by SDS - PAGE
• Concentration: 1 mg/ml (determined by Bradford assay)
• Storage: Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.

Gene Information

• Gene Name: EBAG9 estrogen receptor binding site associated, antigen, 9 [ Homo sapiens ]
• Synonyms: EBAG9; estrogen receptor binding site associated, antigen, 9; EB9; PDAF; RCAS1; estrogen receptor binding site associated antigen 9; cancer associated surface antigen; Receptor-binding cancer antigen expressed on SiSo cells; Cancer-associated surface antigen RCAS1; Estrogen receptor-binding fragment-associated gene 9 protein
• Gene ID: 9166
• mRNA Refseq: NM_004215
• Protein Refseq: NP_004206
• MIM: 605772
• UniProt ID: O00559
• Chromosome Location: 8q23
• Function: apoptotic protease activator activity