Recombinant Human ETV6 Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: ETV6-861H
• Product Overview: ETV6 MS Standard C13 and N15-labeled recombinant protein (NP_001978) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: This gene encodes an ETS family transcription factor. The product of this gene contains two functional domains: a N-terminal pointed (PNT) domain that is involved in protein-protein interactions with itself and other proteins, and a C-terminal DNA-binding domain. Gene knockout studies in mice suggest that it is required for hematopoiesis and maintenance of the developing vascular network. This gene is known to be involved in a large number of chromosomal rearrangements associated with leukemia and congenital fibrosarcoma.
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 53 kDa
• AA Sequence: MSETPAQCSIKQERISYTPPESPVP SYASSTPLHVPVPRALRMEEDSIRL PAHLRLQPIYWSRDDVAQWLKWAEN EFSLRPIDSNTFEMNGKALLLLTKE DFRYRSPHSGDVLYELLQHILKQRK PRILFSPFFHPGNSIHTQPEVILHQ NHEEDNCVQRTPRPSVDNVHHNPPT IELLHRSRSPITTNHRPSPDPEQRP LRSPLDNMIRRLSPAERAQGPRPHQ ENNHQESYPLSVSPMENNHCPASSE SHPKPSSPRQESTRVIQLMPSPIMH PLILNPRHSVDFKQSRLSEDGLHRE GKPINLSHREDLAYMNHIMVSVSPP EEHAMPIGRIADCRLLWDYVYQLLS DSRYENFIRWEDKESKIFRIVDPNG LARLWGNHKNRTNMTYEKMSRALRH YYKLNIIRKEPGQRLLFRFMKTPDE IMSGRTDRLEHLESQELDEQIYQED ECSGPTRTRPLEQKLISEEDLAAND ILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: ETV6 ets variant 6 [ Homo sapiens (human) ]
• Official Symbol: ETV6
• Synonyms: ETV6; ets variant 6; ets variant gene 6 (TEL oncogene); transcription factor ETV6; TEL; TEL oncogene; TEL1 oncogene; ETS-related protein Tel1; ETS translocation variant 6; TEL/ABL
• Gene ID: 2120
• mRNA Refseq: NM_001987
• Protein Refseq: NP_001978
• MIM: 600618
• UniProt ID: P41212