Recombinant Human EXT2 Protein, GST-tagged

• Cat.No.: EXT2-3585H
• Product Overview: Human EXT2 full-length ORF ( NP_000392.1, 1 a.a. - 718 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: This gene encodes one of two glycosyltransferases involved in the chain elongation step of heparan sulfate biosynthesis. Mutations in this gene cause the type II form of multiple exostoses. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene. [provided by RefSeq, Jul 2008]
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 108.7 kDa
• AA Sequence: MCASVKYNIRGPALIPRMKTKHRIY YITLFSIVLLGLIATGMFQFWPHSI ESSNDWNVEKRSIRDVPVVRLPADS PIPERGDLSCRMHTCFDVYRCGFNP KNKIKVYIYALKKYVDDFGVSVSNT ISREYNELLMAISDSDYYTDDINRA CLFVPSIDVLNQNTLRIKETAQAMA QLSRWDRGTNHLLFNMLPGGPPDYN TALDVPRDRALLAGGGFSTWTYRQG YDVSIPVYSPLSAEVDLPEKGPGPR QYFLLSSQVGLHPEYREDLEALQVK HGESVLVLDKCTNLSEGVLSVRKRC HKHQVFDYPQVLQEATFCVVLRGAR LGQAVLSDVLQAGCVPVVIADSYIL PFSEVLDWKRASVVVPEEKMSDVYS ILQSIPQRQIEEMQRQARWFWEAYF QSIKAIALATLQIINDRIYPYAAIS YEEWNDPPAVKWGSVSNPLFLPLIP PQSQGFTAIVLTYDRVESLFRVITE VSKVPSLSKLLVVWNNQNKNPPEDS LWPKIRVPLKVVRTAENKLSNRFFP YDEIETEAVLAIDDDIIMLTSDELQ FGYEVWREFPDRLVGYPGRLHLWDH EMNKWKYESEWTNEVSMVLTGAAFY HKYFNYLYTYKMPGDIKNWVDAHMN CEDIAMNFLVANVTGKAVIKVTPRK KFKCPECTAIDGLSLDQTHMVERSE CINKFASVFGTMPLKVVEHRADPVL YKDDFPEKLKSFPNIGSL
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: EXT2 exostosin 2 [ Homo sapiens ]
• Official Symbol: EXT2
• Synonyms: EXT2; exostosin 2; exostoses (multiple) 2; exostosin-2; Glucuronosyl N acetylglucosaminyl proteoglycan 4 alpha N acetylglucosaminyltransferase; N acetylglucosaminyl proteoglycan 4 beta glucuronosyltransferase; SOTV; multiple exostoses protein 2; putative tumor suppressor protein EXT2; N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase; glucuronosyl-N-acetylglucosaminyl-proteoglycan/N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase
• Gene ID: 2132
• mRNA Refseq: NM_000401
• Protein Refseq: NP_000392
• MIM: 608210
• UniProt ID: Q93063