Recombinant Human EYA3 Protein, GST-tagged

• Cat.No.: EYA3-3593H
• Product Overview: Human EYA3 full-length ORF ( ABZ92386.1, 1 a.a. - 536 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: This gene encodes a member of the eyes absent (EYA) family of proteins. The encoded protein may act as a transcriptional activator and have a role during development. It can act as a mediator of chemoresistance and cell survival in Ewing sarcoma cells, where this gene is up-regulated via a micro-RNA that binds to the 3' UTR of the transcript. A similar protein in mice acts as a transcriptional activator. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Sep 2013]
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 59 kDa
• AA Sequence: MEEEQDLPEQPVKKAKMQESGEQTI SQVSNPDVSDQKPETSSLASNLPMS EEIMTCTDYIPRSSNDYTSQMYSAK PYAHILSVPVSETAYPGQTQYQTLQ QTQPYAVYPQATQTYGLPPFASSTN ASLISTSSTIANIPAAAVASISNQD YPTYTILGQNQYQACYPSSSFGVTG QTNSDAESTTLAATTYQSEKPSVMA PAPAAQRLSSGDPSTSPSLSQTTPS KDTDDQSRKNMTSKNRGKRKADATS SQDSELERVFLWDLDETIIIFHSLL TGSYAQKYGKDPTVVIGSGLTMEEM IFEVADTHLFFNDLEECDQVHVEDV ASDDNGQDLSNYSFSTDGFSGSGGS GSHGSSVGVQGGVDWMRKLAFRYRK VREIYDKHKSNVGGLLSPQRKEALQ RLRAEIEVLTDSWLGTALKSLLLIQ SRKNCVNVLITTTQLVPALAKVLLY GLGEIFPIENIYSATKIGKESCFER IVSRFGKKVTYVVIGDGRDEEIAAK QQLYFLDMEALGCQLEPTALILFIQ LSGNLSNYNKL
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: EYA3 eyes absent homolog 3 (Drosophila) [ Homo sapiens ]
• Official Symbol: EYA3
• Synonyms: EYA3; eyes absent homolog 3 (Drosophila); eyes absent (Drosophila) homolog 3; eyes absent homolog 3; DKFZp686C132; eyes absent 3
• Gene ID: 2140
• mRNA Refseq: NM_001990
• Protein Refseq: NP_001981
• MIM: 601655
• UniProt ID: Q99504